Chicago O Hare International offers nonstop service to 555 destinations, served by 48 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Milwaukee | MKE | USA | 107 km | 1h 5m | AA, UA |
| South Bend | SBN | USA | 135 km | 1h 7m | AA, UA |
| Madison | MSN | USA | 174 km | 1h 11m | AA, UA |
| Bloomington | BMI | USA | 186 km | 1h 1m | AA |
| Muskegon | MKG | USA | 190 km | 0h 50m | KG |
| Lafayette | LAF | USA | 191 km | 0h 59m | UA |
| Kalamazoo | AZO | USA | 196 km | 1h 10m | AA |
| Peoria | PIA | USA | 208 km | 1h 12m | AA, UA |
| Champaign | CMI | USA | 217 km | 1h 8m | AA |
| Grand Rapids | GRR | USA | 219 km | 1h 12m | AA, UA |
| Moline | MLI | USA | 224 km | 1h 14m | AA, UA |
| Decatur | DEC | USA | 251 km | 1h 10m | UA |
| Fort Wayne | FWA | USA | 252 km | 1h 17m | AA, UA |
| Appleton | ATW | USA | 258 km | 1h 16m | AA, UA |
| Green Bay | GRB | USA | 280 km | 1h 15m | AA, UA |
| Springfield | SPI | USA | 280 km | 1h 9m | AA |
| Indianapolis | IND | USA | 285 km | 1h 16m | AA, UA |
| Lansing | LAN | USA | 287 km | 1h 11m | AA |
| Manistee | MBL | USA | 288 km | 1h 20m | LF |
| Burlington | BRL | USA | 299 km | 1h 25m | LF |
| Cedar Rapids | CID | USA | 314 km | 1h 20m | AA, UA |
| Wausau | CWA | USA | 343 km | 1h 20m | AA |
| La Crosse | LSE | USA | 345 km | 1h 26m | AA |
| Saginaw | MBS | USA | 356 km | 1h 23m | UA |
| Quincy | UIN | USA | 357 km | 1h 25m | LF |
| Flint | FNT | USA | 359 km | 1h 22m | AA, UA |
| Traverse City | TVC | USA | 359 km | 1h 24m | AA, UA |
| Waterloo | ALO | USA | 376 km | 1h 26m | AA |
| Detroit | DTW | USA | 377 km | 1h 30m | AA, DL, UA |
| Dayton | DAY | USA | 386 km | 1h 26m | AA, UA |
| Saint Louis | STL | USA | 415 km | 1h 30m | AA, UA |
| Rhinelander | RHI | USA | 424 km | 1h 24m | UA |
| Cincinnati | CVG | USA | 425 km | 1h 30m | AA, UA |
| Rochester | RST | USA | 431 km | 1h 30m | AA |
| Eau Claire | EAU | USA | 432 km | 1h 29m | UA |
| Evansville | EVV | USA | 437 km | 1h 25m | AA |
| Kirksville | IRK | USA | 442 km | 1h 30m | LF |
| Louisville | SDF | USA | 460 km | 1h 35m | AA, UA |
| Mason City | MCW | USA | 464 km | 1h 30m | UA |
| Pellston | PLN | USA | 471 km | 1h 29m | UA |
| Owensboro | OWB | USA | 474 km | 1h 35m | LF, UA |
| Columbus | CMH | USA | 476 km | 1h 34m | AA, UA |
| Marion | MWA | USA | 478 km | 1h 33m | AA, LF |
| Des Moines | DSM | USA | 480 km | 1h 34m | AA, UA |
| Marquette | MQT | USA | 488 km | 1h 33m | AA |
| Columbia | COU | USA | 507 km | 1h 34m | AA, UA |
| Cleveland | CLE | USA | 508 km | 1h 32m | AA, UA |
| Lexington | LEX | USA | 520 km | 1h 36m | AA, UA |
| Fort Dodge | FOD | USA | 522 km | 1h 35m | UA |
| Ironwood | IWD | USA | 535 km | 1h 15m | KG |
| Minneapolis | MSP | USA | 537 km | 1h 38m | AA, DL, SY, UA |
| Cape Girardeau | CGI | USA | 546 km | 1h 35m | LF |
| Sault Ste. Marie | CIU | USA | 548 km | 1h 32m | UA |
| Paducah | PAH | USA | 550 km | 1h 30m | UA |
| Akron | CAK | USA | 553 km | 1h 39m | AA, UA |
| Hancock | CMX | USA | 578 km | 1h 36m | UA |
| Duluth | DLH | USA | 638 km | 1h 50m | UA |
| Erie | ERI | USA | 639 km | 1h 42m | AA |
| Kansas City | MCI | USA | 648 km | 1h 48m | AA, UA |
| Nashville | BNA | USA | 657 km | 1h 47m | AA, UA |
| Pittsburgh | PIT | USA | 661 km | 1h 40m | AA, UA |
| Charleston | CRW | USA | 669 km | 1h 50m | UA |
| Omaha | OMA | USA | 670 km | 1h 47m | AA, UA |
| Sioux City | SUX | USA | 701 km | 1h 53m | UA |
| Toronto | YYZ | Canada | 703 km | 1h 48m | AA, AC, UA |
| Springfield | SGF | USA | 706 km | 1h 50m | AA, UA |
| Clarksburg | CKB | USA | 713 km | 1h 44m | UA |
| Jackson | MKL | USA | 713 km | 1h 50m | KG |
| Toronto | YTZ | Canada | 719 km | 1h 46m | AC, PD |
| Morgantown | MGW | USA | 721 km | 1h 40m | UA |
| Sioux Falls | FSD | USA | 744 km | 1h 56m | AA, UA |
| Lincoln | LNK | USA | 750 km | 1h 58m | AA, UA |
| Buffalo | BUF | USA | 761 km | 1h 48m | AA, UA |
| Knoxville | TYS | USA | 764 km | 1h 51m | AA, UA |
| Bristol, VA/Johnson City/Kingsport | TRI | USA | 772 km | 1h 49m | AA |
| Joplin | JLN | USA | 779 km | 2h 0m | UA |
| Johnstown | JST | USA | 783 km | 1h 42m | UA |
| Lewisburg | LWB | USA | 787 km | 1h 54m | AA |
| Memphis | MEM | USA | 790 km | 1h 58m | AA, UA |
| Chattanooga | CHA | USA | 805 km | 1h 52m | AA, UA |
| Manhattan | MHK | USA | 805 km | 1h 59m | AA |
| Huntsville | HSV | USA | 819 km | 1h 54m | AA, UA |
| Bentonville | XNA | USA | 839 km | 2h 0m | AA, UA |
| State College | SCE | USA | 849 km | 1h 55m | UA |
| Rochester | ROC | USA | 850 km | 1h 55m | AA, UA |
| Roanoke | ROA | USA | 854 km | 2h 1m | AA, UA |
| Asheville | AVL | USA | 862 km | 1h 59m | AA, UA |
| Staunton | SHD | USA | 870 km | 2h 4m | AA |
| Little Rock | LIT | USA | 888 km | 2h 3m | AA, UA |
| Fargo | FAR | USA | 896 km | 2h 13m | AA, UA |
| Salina | SLN | USA | 899 km | 2h 10m | UA |
| Lynchburg | LYH | USA | 907 km | 2h 6m | UA |
| Charlottesville | CHO | USA | 911 km | 2h 8m | AA, UA |
| Greenville | GSP | USA | 929 km | 2h 2m | AA, UA |
| Kearney | EAR | USA | 938 km | 2h 10m | UA |
| Birmingham | BHM | USA | 939 km | 2h 4m | AA, UA |
| Tulsa | TUL | USA | 942 km | 2h 10m | AA, UA |
| Wichita | ICT | USA | 945 km | 2h 14m | AA, UA |
| Dulles | IAD | USA | 947 km | 2h 2m | UA |
| Greensboro/High Point | GSO | USA | 948 km | 2h 5m | AA, UA |
| Middletown | MDT | USA | 956 km | 2h 0m | AA, UA |
| Charlotte | CLT | USA | 964 km | 2h 9m | AA, UA |
| Atlanta | ATL | USA | 973 km | 2h 6m | AA, DL, F9, UA |
| Syracuse | SYR | USA | 976 km | 2h 0m | AA, UA |
| Washington | DCA | USA | 984 km | 2h 4m | AA, UA |
| Lancaster | LNS | USA | 996 km | 2h 6m | UA |
| Baltimore | BWI | USA | 999 km | 2h 7m | AA, F9, UA |
| Wilkes-Barre | AVP | USA | 1,015 km | 2h 5m | AA, UA |
| Richmond | RIC | USA | 1,032 km | 2h 12m | AA, UA |
| Raleigh/Durham | RDU | USA | 1,039 km | 2h 12m | AA, UA |
| Allentown | ABE | USA | 1,053 km | 2h 10m | AA, UA |
| Ottawa | YOW | Canada | 1,053 km | 2h 18m | UA |
| Columbia | CAE | USA | 1,072 km | 2h 11m | AA, UA |
| Augusta | AGS | USA | 1,088 km | 2h 10m | AA |
| Philadelphia | PHL | USA | 1,090 km | 2h 13m | AA, F9, UA |
| Oklahoma City | OKC | USA | 1,114 km | 2h 31m | AA, UA |
| Winnipeg | YWG | Canada | 1,137 km | 2h 48m | UA |
| Bismarck | BIS | USA | 1,152 km | 2h 31m | AA |
| Norfolk | ORF | USA | 1,152 km | 2h 25m | AA, UA |
| New York | EWR | USA | 1,156 km | 2h 19m | AA, UA |
| Albany | ALB | USA | 1,162 km | 2h 15m | AA, UA |
| Shreveport | SHV | USA | 1,179 km | 2h 40m | UA |
| New York | LGA | USA | 1,180 km | 2h 16m | AA, DL, UA |
| Westchester County | HPN | USA | 1,188 km | 2h 20m | AA |
| New York | JFK | USA | 1,190 km | 2h 25m | AA, B6, DL |
| Montreal | YUL | Canada | 1,202 km | 2h 20m | AA, AC, UA |
| Myrtle Beach | MYR | USA | 1,212 km | 2h 31m | AA, UA |
| Wilmington | ILM | USA | 1,223 km | 2h 22m | AA, UA |
| Charleston | CHS | USA | 1,224 km | 2h 23m | AA, UA |
| Burlington | BTV | USA | 1,228 km | 2h 22m | AA, UA |
| Savannah | SAV | USA | 1,242 km | 2h 25m | AA, UA |
| New Haven | HVN | USA | 1,252 km | 2h 23m | XP |
| Rapid City | RAP | USA | 1,254 km | 2h 35m | AA, UA |
| Hilton Head | HHH | USA | 1,256 km | 2h 25m | AA, UA |
| Hartford | BDL | USA | 1,260 km | 2h 21m | AA, UA |
| Pensacola | PNS | USA | 1,277 km | 2h 29m | AA, UA |
| Fort Walton Beach | VPS | USA | 1,279 km | 2h 35m | AA |
| Dallas | DFW | USA | 1,290 km | 2h 44m | AA, F9, UA |
| Panama City | ECP | USA | 1,303 km | 2h 33m | AA, UA |
| New Orleans | MSY | USA | 1,347 km | 2h 33m | AA, UA |
| Manchester | MHT | USA | 1,356 km | 2h 31m | AA |
| Providence | PVD | USA | 1,365 km | 2h 30m | AA, UA |
| Jacksonville | JAX | USA | 1,390 km | 2h 33m | AA, UA |
| Boston | BOS | USA | 1,393 km | 2h 32m | AA, B6, DL, UA |
| Quebec | YQB | Canada | 1,417 km | 2h 33m | AA, UA |
| Denver | DEN | USA | 1,429 km | 2h 50m | AA, F9, UA |
| Martha's Vineyard | MVY | USA | 1,438 km | 2h 33m | AA |
| Portland | PWM | USA | 1,448 km | 2h 34m | AA, UA |
| Hyannis | HYA | USA | 1,462 km | 2h 35m | AA |
| Colorado Springs | COS | USA | 1,466 km | 3h 5m | AA, UA |
| Nantucket | ACK | USA | 1,486 km | 2h 45m | AA, UA |
| Houston | IAH | USA | 1,488 km | 2h 56m | AA, F9, UA |
| Austin | AUS | USA | 1,572 km | 2h 58m | AA, UA |
| Bangor | BGR | USA | 1,574 km | 2h 49m | AA, UA |
| Orlando | MCO | USA | 1,617 km | 2h 51m | AA, F9, UA |
| Vail | EGE | USA | 1,621 km | 3h 10m | AA, UA |
| Hayden | HDN | USA | 1,624 km | 3h 9m | AA, UA |
| Tampa | TPA | USA | 1,627 km | 2h 51m | AA, F9, UA |
| Aspen | ASE | USA | 1,630 km | 3h 26m | AA, UA |
| Gunnison | GUC | USA | 1,660 km | 3h 10m | UA |
| San Antonio | SAT | USA | 1,677 km | 3h 4m | AA, UA |
| Sarasota | SRQ | USA | 1,690 km | 2h 57m | AA, UA |
| Billings | BIL | USA | 1,706 km | 3h 16m | AA, UA |
| Santa Fe | SAF | USA | 1,725 km | 3h 29m | AA, UA |
| Cody | COD | USA | 1,733 km | 3h 17m | UA |
| Montrose | MTJ | USA | 1,739 km | 3h 49m | UA |
| Albuquerque | ABQ | USA | 1,798 km | 3h 17m | AA, UA |
| Fort Myers | RSW | USA | 1,803 km | 3h 3m | AA, F9, UA |
| West Palm Beach | DJT | USA | 1,840 km | 3h 12m | AA, UA |
| Jackson | JAC | USA | 1,870 km | 3h 22m | AA, UA |
| Fort Lauderdale | FLL | USA | 1,902 km | 3h 12m | AA, B6, F9, UA |
| Bozeman | BZN | USA | 1,908 km | 3h 27m | AA, UA |
| Miami | MIA | USA | 1,926 km | 3h 17m | AA, UA |
| Harlingen | HRL | USA | 1,962 km | 3h 36m | AA |
| Idaho Falls | IDA | USA | 1,978 km | 3h 39m | AA, UA |
| El Paso | ELP | USA | 1,991 km | 3h 41m | AA, UA |
| Halifax | YHZ | Canada | 1,993 km | 3h 25m | AA, UA |
| Provo | PVU | USA | 2,003 km | 3h 52m | AA |
| Salt Lake City | SLC | USA | 2,011 km | 3h 42m | AA, DL, UA |
| Key West | EYW | USA | 2,014 km | 3h 26m | AA, UA |
| Nassau | NAS | Bahamas | 2,109 km | 3h 32m | AA, UA |
| Monterrey | MTY | Mexico | 2,117 km | 3h 40m | UA, VB |
| Missoula | MSO | USA | 2,143 km | 3h 56m | AA, UA |
| Sun Valley | SUN | USA | 2,158 km | 4h 12m | AA, UA |
| Kalispell | FCA | USA | 2,175 km | 3h 57m | AA, UA |
| Calgary | YYC | Canada | 2,229 km | 3h 55m | AA, UA, WS |
| Saint George | SGU | USA | 2,260 km | 3h 55m | UA |
| Edmonton | YEG | Canada | 2,284 km | 3h 47m | UA |
| Boise | BOI | USA | 2,312 km | 3h 58m | AA, UA |
| Tucson | TUS | USA | 2,312 km | 3h 59m | AA, UA |
| Phoenix | PHX | USA | 2,316 km | 3h 59m | AA, F9, UA |
| Cancun | CUN | Mexico | 2,323 km | 3h 57m | AA, F9, UA |
| Cozumel | CZM | Mexico | 2,381 km | 4h 1m | AA, UA |
| Spokane | GEG | USA | 2,410 km | 4h 13m | AA, UA |
| Las Vegas | LAS | USA | 2,436 km | 4h 11m | AA, F9, UA |
| Grand Cayman Island | GCM | Cayman Islands | 2,589 km | 4h 3m | AA, UA |
| Queretaro | QRO | Mexico | 2,634 km | 4h 2m | AA, Y4 |
| Leon/Guanajuato | BJX | Mexico | 2,652 km | 4h 8m | Y4 |
| Palm Springs | PSP | USA | 2,658 km | 4h 36m | AA, UA |
| Providenciales | PLS | Turks and Caicos Islands | 2,675 km | 4h 10m | AA, UA |
| Reno | RNO | USA | 2,690 km | 4h 38m | UA |
| Belize City | BZE | Belize | 2,709 km | 4h 24m | UA |
| Mexico City | MEX | Mexico | 2,712 km | 4h 29m | AA, AM, UA, VB, Y4 |
| Puebla | PBC | Mexico | 2,718 km | 4h 19m | Y4 |
| Ontario | ONT | USA | 2,735 km | 4h 32m | AA, UA |
| Morelia | MLM | Mexico | 2,748 km | 3h 53m | Y4 |
| Seattle | SEA | USA | 2,768 km | 4h 44m | AA, AS, DL, UA |
| Montego Bay | MBJ | Jamaica | 2,769 km | 4h 10m | AA, UA |
| San Diego | SAN | USA | 2,773 km | 4h 34m | AA, AS, UA |
| Santa Ana | SNA | USA | 2,776 km | 4h 33m | AA, UA |
| Fresno | FAT | USA | 2,784 km | 4h 31m | UA |
| Guadalajara | GDL | Mexico | 2,784 km | 4h 24m | AM, VB, Y4 |
| Portland | PDX | USA | 2,798 km | 4h 38m | AA, AS, UA |
| Los Angeles | LAX | USA | 2,807 km | 4h 37m | AA, DL, F9, UA |
| Vancouver | YVR | Canada | 2,838 km | 4h 47m | AA, AC, UA |
| Eugene | EUG | USA | 2,864 km | 4h 45m | UA |
| Sacramento | SMF | USA | 2,867 km | 4h 45m | AA, UA |
| Puerto Vallarta | PVR | Mexico | 2,868 km | 4h 45m | AA, UA |
| Santa Barbara | SBA | USA | 2,900 km | 4h 48m | UA |
| San Jose Cabo | SJD | Mexico | 2,906 km | 4h 54m | AA, UA |
| San Jose | SJC | USA | 2,943 km | 4h 47m | UA |
| San Francisco | SFO | USA | 2,972 km | 4h 55m | AA, UA |
| Ixtapa/Zihuatanejo | ZIH | Mexico | 2,993 km | 4h 58m | UA |
| Guatemala City | GUA | Guatemala | 3,046 km | 4h 41m | AA, AV, UA |
| Punta Cana | PUJ | Dominican Republic | 3,188 km | 4h 38m | AA, DM, UA |
| San Juan | SJU | Puerto Rico | 3,333 km | 4h 48m | AA, F9, UA |
| Saint Thomas | STT | U.S. Virgin Islands | 3,404 km | 4h 51m | AA, UA |
| Saint Croix | STX | U.S. Virgin Islands | 3,472 km | 4h 40m | AA |
| Guanacaste | LIR | Costa Rica | 3,484 km | 5h 7m | AA, UA |
| Sint Maarten | SXM | Sint Maarten | 3,545 km | 5h 13m | AA, UA |
| San Jose | SJO | Costa Rica | 3,561 km | 5h 13m | UA |
| Aruba | AUA | Aruba | 3,698 km | 5h 16m | AA, UA |
| Panama City | PTY | Panama | 3,740 km | 5h 23m | CM |
| Curacao | CUR | Curaçao | 3,778 km | 5h 0m | AA |
| Saint Lucia | UVF | Saint Lucia | 4,068 km | 5h 33m | UA |
| Bogota | BOG | Colombia | 4,349 km | 6h 10m | AV |
| Fairbanks | FAI | USA | 4,482 km | 6h 41m | UA |
| Anchorage | ANC | USA | 4,580 km | 6h 52m | AA, AS, UA |
| Reykjavik | KEF | Iceland | 4,736 km | 6h 15m | FI, UA |
| Shannon | SNN | Ireland | 5,778 km | 7h 25m | UA |
| Dublin | DUB | Ireland | 5,913 km | 7h 25m | AA, EI, UA |
| Edinburgh | EDI | United Kingdom | 5,974 km | 7h 50m | UA |
| London | LHR | United Kingdom | 6,362 km | 7h 50m | AA, BA, UA |
| Lisbon | LIS | Portugal | 6,452 km | 8h 5m | TP |
| Amsterdam | AMS | Netherlands | 6,630 km | 7h 50m | KL, UA |
| Paris | CDG | France | 6,684 km | 8h 10m | AA, AF, UA |
| Brussels | BRU | Belgium | 6,694 km | 8h 0m | UA |
| Kahului | OGG | USA | 6,734 km | 9h 24m | AA, UA |
| Madrid | MAD | Spain | 6,761 km | 8h 13m | AA, IB |
| Kailua-Kona | KOA | USA | 6,780 km | 9h 11m | UA |
| Honolulu | HNL | USA | 6,828 km | 9h 12m | AA, UA |
| Copenhagen | CPH | Denmark | 6,872 km | 8h 10m | SK |
| Frankfurt | FRA | Germany | 6,989 km | 8h 20m | DE, LH, UA |
| Barcelona | BCN | Spain | 7,111 km | 8h 35m | AA, UA |
| Helsinki | HEL | Finland | 7,139 km | 8h 45m | AY |
| Zurich | ZRH | Switzerland | 7,151 km | 8h 50m | LX, UA |
| Milan | MXP | Italy | 7,278 km | 8h 45m | UA |
| Munich | MUC | Germany | 7,289 km | 8h 30m | LH, UA |
| Warsaw | WAW | Poland | 7,540 km | 9h 5m | LO |
| Vienna | VIE | Austria | 7,586 km | 8h 45m | OS |
| Krakow | KRK | Poland | 7,628 km | 9h 5m | LO |
| Rome | FCO | Italy | 7,762 km | 9h 15m | AA, AZ, UA |
| Naples | NAP | Italy | 7,958 km | 9h 33m | AA |
| Belgrade | BEG | Republic of Serbia | 8,042 km | 9h 45m | JU |
| Sao Paulo | GRU | Brazil | 8,402 km | 10h 13m | UA |
| Athens | ATH | Greece | 8,791 km | 10h 20m | AA, UA |
| Istanbul | IST | Turkiye | 8,809 km | 10h 25m | TK |
| Cairo | CAI | Egypt | 9,895 km | 11h 10m | MS |
| Tel Aviv-Yafo | TLV | Israel | 9,945 km | 11h 25m | UA |
| Amman | AMM | Jordan | 10,035 km | 11h 35m | RJ |
| Tokyo | NRT | Japan | 10,096 km | 13h 30m | AA, JL, NH, UA |
| Tokyo | HND | Japan | 10,147 km | 13h 30m | JL, NH, UA |
| Seoul | ICN | Republic of Korea | 10,545 km | 14h 40m | KE |
| Doha | DOH | Qatar | 11,480 km | 13h 20m | QR |
| Dubai | DXB | United Arab Emirates | 11,661 km | 13h 25m | EK |
| Abu Dhabi | AUH | United Arab Emirates | 11,709 km | 13h 30m | EY |
| Taipei | TPE | Taiwan | 12,001 km | 15h 50m | BR |
| Addis Ababa | ADD | Ethiopia | 12,193 km | 13h 45m | ET |
| Hong Kong | HKG | Hong Kong SAR | 12,541 km | 15h 55m | CX |
| Manila | MNL | Philippines | 13,086 km | 16h 40m | PR |