President Donald J. Trump International Airport offers nonstop service to 86 destinations, served by 12 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Orlando | MCO | USA | 227 km | 1h 0m | WN |
| Marsh Harbour | MHH | Bahamas | 301 km | 1h 0m | UP |
| Charleston | CHS | USA | 687 km | 1h 41m | MX |
| Atlanta | ATL | USA | 877 km | 1h 53m | DL |
| Charlotte | CLT | USA | 949 km | 2h 3m | AA |
| Asheville | AVL | USA | 997 km | 1h 53m | G4 |
| Raleigh/Durham | RDU | USA | 1,026 km | 2h 8m | MX |
| Norfolk | ORF | USA | 1,190 km | 2h 15m | MX |
| Nashville | BNA | USA | 1,219 km | 2h 20m | WN |
| Richmond | RIC | USA | 1,228 km | 2h 13m | MX |
| Washington | DCA | USA | 1,379 km | 2h 25m | AA, B6 |
| Dulles | IAD | USA | 1,382 km | 2h 25m | UA |
| Baltimore | BWI | USA | 1,422 km | 2h 25m | WN |
| Cincinnati | CVG | USA | 1,436 km | 2h 38m | G4 |
| Columbus | CMH | USA | 1,499 km | 2h 40m | MX |
| Wilmington | ILG | USA | 1,500 km | 2h 35m | XP |
| Atlantic City | ACY | USA | 1,506 km | 2h 50m | MX |
| Philadelphia | PHL | USA | 1,530 km | 2h 44m | AA, F9 |
| Pittsburgh | PIT | USA | 1,532 km | 2h 37m | G4, WN |
| Houston | IAH | USA | 1,537 km | 2h 54m | UA |
| Indianapolis | IND | USA | 1,555 km | 2h 45m | WN |
| Akron | CAK | USA | 1,583 km | 2h 46m | MX |
| New York | EWR | USA | 1,646 km | 2h 54m | B6, UA |
| Saint Louis | STL | USA | 1,646 km | 2h 55m | WN |
| New York | JFK | USA | 1,653 km | 2h 47m | B6, DL |
| New York | LGA | USA | 1,664 km | 2h 50m | AA, B6, DL |
| Islip | ISP | USA | 1,692 km | 2h 40m | B6, WN |
| Westchester County | HPN | USA | 1,700 km | 2h 51m | B6 |
| Detroit | DTW | USA | 1,747 km | 3h 0m | DL |
| New Haven | HVN | USA | 1,747 km | 2h 52m | MX, XP |
| Dallas | DFW | USA | 1,774 km | 3h 21m | AA |
| Buffalo | BUF | USA | 1,807 km | 2h 55m | WN |
| Hartford | BDL | USA | 1,821 km | 2h 52m | B6 |
| Chicago | ORD | USA | 1,840 km | 3h 28m | AA, UA |
| Providence | PVD | USA | 1,847 km | 2h 53m | B6, WN |
| Grand Rapids | GRR | USA | 1,863 km | 3h 4m | G4 |
| Toronto | YYZ | Canada | 1,886 km | 3h 12m | AC, PD |
| Boston | BOS | USA | 1,926 km | 3h 10m | AA, B6, DL |
| Montreal | YUL | Canada | 2,158 km | 3h 34m | AC |
| Minneapolis | MSP | USA | 2,334 km | 3h 54m | DL |
| Denver | DEN | USA | 2,701 km | 4h 30m | UA, WN |
| Los Angeles | LAX | USA | 3,749 km | 5h 43m | B6, DL |
| San Francisco | SFO | USA | 4,131 km | 6h 23m | UA |