Martha's Vineyard offers nonstop service to 26 destinations, served by 5 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Hyannis | HYA | USA | 41 km | 0h 25m | 9K |
| New Bedford | EWB | USA | 43 km | 0h 24m | 9K |
| Nantucket | ACK | USA | 48 km | 0h 25m | 9K |
| Boston | BOS | USA | 113 km | 0h 50m | 9K, B6 |
| Bedford/Hanscom | BED | USA | 132 km | 0h 39m | TJ |
| Westchester County | HPN | USA | 261 km | 0h 59m | 9K, TJ |
| New York | JFK | USA | 279 km | 1h 5m | 9K, B6, DL |
| New York | LGA | USA | 282 km | 1h 20m | AA, DL |
| Teterboro | TEB | USA | 295 km | 1h 3m | TJ |
| Philadelphia | PHL | USA | 426 km | 1h 29m | AA |
| Washington | DCA | USA | 616 km | 1h 44m | AA, B6 |
| Charlotte | CLT | USA | 1,132 km | 2h 18m | AA |
| Chicago | ORD | USA | 1,438 km | 2h 50m | AA |