Winnipeg International offers nonstop service to 85 destinations, served by 8 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Red Lake | YRL | Canada | 275 km | 0h 55m | JV |
| The Pas | YQD | Canada | 524 km | 1h 40m | MO |
| Regina | YQR | Canada | 533 km | 1h 40m | WS |
| Thunder Bay | YQT | Canada | 601 km | 1h 30m | WS |
| Flin Flon | YFO | Canada | 612 km | 1h 55m | MO |
| Minneapolis | MSP | USA | 635 km | 1h 38m | DL |
| Thompson | YTH | Canada | 657 km | 1h 55m | MO |
| Saskatoon | YXE | Canada | 709 km | 1h 45m | WS |
| Gillam | YGX | Canada | 736 km | 2h 0m | MO |
| Churchill | YYQ | Canada | 1,005 km | 2h 30m | MO |
| Chicago | ORD | USA | 1,137 km | 2h 35m | UA |
| Edmonton | YEG | Canada | 1,191 km | 2h 10m | F8, WS |
| Calgary | YYC | Canada | 1,195 km | 2h 20m | AC, F8, WS |
| Denver | DEN | USA | 1,261 km | 2h 50m | UA |
| Sanikiluaq | YSK | Canada | 1,405 km | 3h 25m | MO |
| London | YXU | Canada | 1,447 km | 2h 15m | WS |
| Rankin Inlet | YRT | Canada | 1,470 km | 2h 30m | MO |
| Toronto | YYZ | Canada | 1,507 km | 2h 30m | AC, F8, PD, WS |
| Hamilton | YHM | Canada | 1,517 km | 2h 14m | PD |
| Kelowna | YLW | Canada | 1,585 km | 2h 45m | WS |
| Ottawa | YOW | Canada | 1,691 km | 2h 34m | AC, PD, WS |
| Montreal | YUL | Canada | 1,822 km | 2h 47m | AC |
| Montreal | YHU | Canada | 1,842 km | 2h 40m | PD |
| Vancouver | YVR | Canada | 1,870 km | 3h 20m | AC, F8, WS |
| Victoria | YYJ | Canada | 1,902 km | 3h 10m | WS |
| Atlanta | ATL | USA | 2,089 km | 3h 20m | WS |
| Las Vegas | LAS | USA | 2,109 km | 3h 30m | WS |
| Phoenix | PHX | USA | 2,195 km | 3h 45m | WS |
| Palm Springs | PSP | USA | 2,384 km | 3h 55m | WS |
| Halifax | YHZ | Canada | 2,582 km | 3h 35m | WS |
| Orlando | MCO | USA | 2,739 km | 4h 5m | WS |
| Fort Lauderdale | FLL | USA | 3,025 km | 4h 30m | WS |
| San Jose Cabo | SJD | Mexico | 3,161 km | 4h 55m | WS |
| St. John's | YYT | Canada | 3,231 km | 4h 25m | WS |
| Puerto Vallarta | PVR | Mexico | 3,319 km | 5h 5m | WS |
| Cancun | CUN | Mexico | 3,330 km | 5h 5m | AC, WS |
| Belize City | BZE | Belize | 3,678 km | 5h 20m | WS |
| Huatulco | HUX | Mexico | 3,787 km | 5h 30m | WS |
| Montego Bay | MBJ | Jamaica | 3,886 km | 5h 35m | AC, WS |
| Punta Cana | PUJ | Dominican Republic | 4,322 km | 5h 50m | AC, WS |
| Guanacaste | LIR | Costa Rica | 4,489 km | 6h 20m | WS |
| Reykjavik | KEF | Iceland | 4,496 km | 5h 50m | WS |