Honolulu International Airport offers nonstop service to 114 destinations, served by 17 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Hoolehua | MKK | USA | 88 km | 0h 44m | 9X |
| Kalaupapa | LUP | USA | 99 km | 0h 49m | 9X |
| Lanai | LNY | USA | 117 km | 0h 49m | 9X |
| Kapalua | JHM | USA | 135 km | 1h 0m | 9X |
| Kahului | OGG | USA | 161 km | 0h 44m | AS, WN |
| Kauai Island | LIH | USA | 164 km | 0h 43m | AS, WN |
| Kailua-Kona | KOA | USA | 263 km | 0h 49m | AS, WN |
| Hilo | ITO | USA | 349 km | 0h 56m | AS, WN |
| Christmas Island | CXI | Kiribati | 2,142 km | 3h 20m | FJ |
| Majuro | MAJ | Marshall Islands | 3,667 km | 5h 20m | UA |
| San Francisco | SFO | USA | 3,858 km | 5h 13m | AS, UA |
| Oakland | OAK | USA | 3,876 km | 5h 9m | AS, WN |
| San Jose | SJC | USA | 3,888 km | 5h 13m | AS, WN |
| Sacramento | SMF | USA | 3,961 km | 5h 11m | AS, WN |
| Los Angeles | LAX | USA | 4,112 km | 5h 28m | AA, AS, DL, UA, WN |
| Burbank | BUR | USA | 4,122 km | 5h 20m | AS, WN |
| Long Beach | LGB | USA | 4,134 km | 5h 25m | AS, WN |
| Apia | APW | Samoa | 4,182 km | 5h 50m | FJ |
| Pago Pago | PPG | American Samoa | 4,183 km | 5h 50m | AS |
| Ontario | ONT | USA | 4,188 km | 5h 33m | AS, WN |
| Portland | PDX | USA | 4,188 km | 5h 33m | AS |
| San Diego | SAN | USA | 4,205 km | 5h 30m | AS, WN |
| Seattle | SEA | USA | 4,308 km | 5h 52m | AS, DL |
| Everett | PAE | USA | 4,334 km | 5h 51m | AS |
| Vancouver | YVR | Canada | 4,353 km | 5h 55m | AC, WS |
| Papeete | PPT | French Polynesia | 4,395 km | 5h 50m | AS |
| Las Vegas | LAS | USA | 4,445 km | 5h 44m | AS, WN |
| Anchorage | ANC | USA | 4,468 km | 6h 9m | AS |
| Boise | BOI | USA | 4,563 km | 6h 3m | AS |
| Spokane | GEG | USA | 4,636 km | 6h 9m | AS |
| Phoenix | PHX | USA | 4,695 km | 5h 58m | AA, AS, WN |
| Rarotonga | RAR | Cook Islands | 4,708 km | 6h 20m | AS |
| Salt Lake City | SLC | USA | 4,817 km | 6h 11m | AS, DL |
| Calgary | YYC | Canada | 5,031 km | 6h 40m | WS |
| Nadi | NAN | Fiji | 5,089 km | 6h 50m | FJ |
| Edmonton | YEG | Canada | 5,160 km | 6h 50m | WS |
| Denver | DEN | USA | 5,414 km | 6h 45m | UA |
| Dallas | DFW | USA | 6,090 km | 7h 20m | AA |
| Guam | GUM | Guam | 6,115 km | 7h 43m | UA |
| Tokyo | NRT | Japan | 6,145 km | 8h 45m | JL, NH, ZG |
| Tokyo | HND | Japan | 6,201 km | 9h 20m | AS, DL, JL, NH |
| Houston | IAH | USA | 6,282 km | 7h 35m | UA |
| Minneapolis | MSP | USA | 6,392 km | 7h 49m | DL |
| Nagoya | NGO | Japan | 6,476 km | 8h 45m | JL |
| Osaka | KIX | Japan | 6,624 km | 10h 0m | AS, JL |
| Chicago | ORD | USA | 6,828 km | 8h 8m | AA, UA |
| Auckland | AKL | New Zealand | 7,063 km | 9h 0m | NZ |
| Detroit | DTW | USA | 7,201 km | 8h 37m | DL |
| Atlanta | ATL | USA | 7,243 km | 8h 34m | DL |
| Seoul | ICN | Republic of Korea | 7,365 km | 9h 35m | KE, YP |
| Toronto | YYZ | Canada | 7,482 km | 8h 40m | AC |
| Dulles | IAD | USA | 7,752 km | 9h 16m | UA |
| New York | EWR | USA | 7,985 km | 9h 38m | UA |
| New York | JFK | USA | 8,018 km | 9h 45m | AS, DL |
| Sydney | SYD | Australia | 8,153 km | 10h 45m | AS, QF |
| Boston | BOS | USA | 8,197 km | 9h 42m | DL |
| Manila | MNL | Philippines | 8,532 km | 10h 55m | PR |