Ted Stevens Anchorage International offers nonstop service to 51 destinations, served by 12 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Kenai | ENA | USA | 96 km | 0h 35m | VC |
| Homer | HOM | USA | 189 km | 0h 40m | VC |
| Cordova | CDV | USA | 257 km | 0h 56m | AS |
| Iliamna | ILI | USA | 312 km | 1h 0m | V8 |
| Kodiak | ADQ | USA | 406 km | 1h 4m | AS |
| Fairbanks | FAI | USA | 420 km | 1h 3m | AS |
| King Salmon | AKN | USA | 464 km | 1h 9m | AS, VC |
| Aniak | ANI | USA | 511 km | 1h 15m | |
| Dillingham | DLG | USA | 529 km | 1h 16m | AS |
| Galena | GAL | USA | 530 km | 1h 30m | 5V |
| Unalakleet | UNK | USA | 631 km | 1h 25m | VC |
| Bethel | BET | USA | 641 km | 1h 22m | AS |
| Saint Mary's | KSM | USA | 711 km | 1h 15m | VC |
| Nome | OME | USA | 866 km | 1h 38m | AS |
| Kotzebue | OTZ | USA | 883 km | 1h 37m | AS |
| Sand Point | SDP | USA | 896 km | 2h 5m | VC |
| Juneau | JNU | USA | 918 km | 1h 44m | AS |
| Cold Bay | CDB | USA | 998 km | 2h 5m | VC |
| Prudhoe Bay/Deadhorse | SCC | USA | 1,008 km | 1h 47m | AS |
| Utqiagvik Barrow | BRW | USA | 1,166 km | 1h 59m | AS |
| Saint Paul Island | SNP | USA | 1,234 km | 2h 20m | VC |
| Dutch Harbor | DUT | USA | 1,274 km | 2h 20m | VC |
| Adak Island | ADK | USA | 1,918 km | 3h 10m | AS |
| Vancouver | YVR | Canada | 2,141 km | 3h 15m | AC |
| Seattle | SEA | USA | 2,331 km | 3h 35m | AS, DL |
| Calgary | YYC | Canada | 2,457 km | 3h 40m | WS |
| Portland | PDX | USA | 2,482 km | 3h 40m | AS |
| Spokane | GEG | USA | 2,549 km | 3h 46m | AS |
| Boise | BOI | USA | 2,963 km | 4h 18m | AS |
| Sacramento | SMF | USA | 3,174 km | 4h 29m | AS |
| San Francisco | SFO | USA | 3,247 km | 4h 44m | UA, AS |
| Salt Lake City | SLC | USA | 3,419 km | 4h 40m | DL, AS |
| Las Vegas | LAS | USA | 3,708 km | 5h 12m | AS, WN |
| Los Angeles | LAX | USA | 3,774 km | 5h 22m | AS, DL |
| Denver | DEN | USA | 3,871 km | 5h 18m | UA, AS, WN |
| San Diego | SAN | USA | 3,945 km | 5h 27m | AS |
| Minneapolis | MSP | USA | 4,053 km | 5h 26m | DL, SY, AS |
| Phoenix | PHX | USA | 4,106 km | 5h 34m | AA, AS |
| Honolulu | HNL | USA | 4,468 km | 6h 10m | AS |
| Kahului | OGG | USA | 4,501 km | 6h 22m | AS |
| Chicago | ORD | USA | 4,580 km | 6h 18m | AS, UA, AA |
| Kailua-Kona | KOA | USA | 4,626 km | 6h 27m | AS |
| Detroit | DTW | USA | 4,804 km | 6h 29m | DL |
| Dallas | DFW | USA | 4,897 km | 6h 29m | AA |
| Houston | IAH | USA | 5,255 km | 6h 56m | UA |
| Dulles | IAD | USA | 5,400 km | 6h 57m | UA |
| New York | EWR | USA | 5,423 km | 7h 6m | UA |
| Boston | BOS | USA | 5,442 km | 7h 15m | AS |
| New York | JFK | USA | 5,447 km | 7h 19m | AS |
| Atlanta | ATL | USA | 5,497 km | 6h 57m | DL |
| Frankfurt | FRA | Germany | 7,525 km | 9h 35m | DE |