Lehigh Valley Intl offers nonstop service to 28 destinations, served by 4 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Charlotte | CLT | USA | 772 km | 1h 58m | AA |
| Myrtle Beach | MYR | USA | 832 km | 1h 40m | G4 |
| Chicago | ORD | USA | 1,053 km | 2h 33m | AA, UA |
| Nashville | BNA | USA | 1,101 km | 2h 5m | G4 |
| Atlanta | ATL | USA | 1,115 km | 2h 23m | DL |
| Orlando | SFB | USA | 1,420 km | 2h 28m | G4 |
| Orlando | MCO | USA | 1,457 km | 2h 41m | G4 |
| Melbourne | MLB | USA | 1,471 km | 2h 35m | G4 |
| Saint Petersburg | PIE | USA | 1,561 km | 2h 42m | G4 |
| Sarasota | SRQ | USA | 1,610 km | 2h 50m | G4 |
| Punta Gorda | PGD | USA | 1,638 km | 2h 52m | G4 |
| Fort Myers | RSW | USA | 1,671 km | 2h 59m | G4 |
| Fort Lauderdale | FLL | USA | 1,674 km | 3h 0m | G4 |
| Denver | DEN | USA | 2,477 km | 3h 50m | G4 |