Eglin Afb offers nonstop service to 50 destinations, served by 6 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Atlanta | ATL | USA | 401 km | 1h 17m | DL |
| Memphis | MEM | USA | 598 km | 1h 25m | G4 |
| Nashville | BNA | USA | 625 km | 1h 30m | WN |
| Knoxville | TYS | USA | 635 km | 1h 21m | G4 |
| Asheville | AVL | USA | 663 km | 1h 25m | G4 |
| Little Rock | LIT | USA | 709 km | 1h 26m | G4 |
| Shreveport | SHV | USA | 724 km | 1h 34m | G4 |
| Charlotte | CLT | USA | 741 km | 1h 48m | AA |
| Miami | MIA | USA | 806 km | 1h 42m | AA |
| Evansville | EVV | USA | 842 km | 1h 38m | G4 |
| Houston | HOU | USA | 846 km | 1h 50m | WN |
| Louisville | SDF | USA | 855 km | 1h 45m | G4 |
| Lexington | LEX | USA | 855 km | 1h 39m | G4 |
| Belleville | BLV | USA | 941 km | 1h 46m | G4 |
| Huntington | HTS | USA | 946 km | 1h 46m | G4 |
| Bentonville | XNA | USA | 963 km | 1h 51m | G4 |
| Cincinnati | CVG | USA | 965 km | 1h 52m | G4 |
| Springfield | SGF | USA | 979 km | 1h 54m | G4 |
| Saint Louis | STL | USA | 980 km | 1h 55m | WN |
| Dallas | DAL | USA | 1,010 km | 2h 0m | WN |
| Indianapolis | IND | USA | 1,023 km | 1h 56m | G4 |
| Dallas | DFW | USA | 1,028 km | 2h 22m | AA |
| Columbia | COU | USA | 1,058 km | 1h 59m | G4 |
| Austin | AUS | USA | 1,068 km | 2h 15m | WN |
| Tulsa | TUL | USA | 1,073 km | 2h 2m | G4 |
| Columbus | LCK | USA | 1,085 km | 1h 58m | G4 |
| Clarksburg | CKB | USA | 1,133 km | 1h 58m | G4 |
| Peoria | PIA | USA | 1,163 km | 2h 2m | G4 |
| Oklahoma City | OKC | USA | 1,166 km | 2h 5m | G4 |
| Kansas City | MCI | USA | 1,227 km | 2h 15m | G4, WN |
| Akron | CAK | USA | 1,244 km | 2h 8m | G4 |
| Pittsburgh | PIT | USA | 1,246 km | 2h 9m | G4, WN |
| Dulles | IAD | USA | 1,253 km | 2h 12m | G4 |
| Chicago | MDW | USA | 1,257 km | 2h 18m | G4 |
| Washington | DCA | USA | 1,270 km | 2h 17m | AA |
| Wichita | ICT | USA | 1,278 km | 2h 15m | G4 |
| Chicago | ORD | USA | 1,279 km | 2h 43m | AA |
| Baltimore | BWI | USA | 1,319 km | 2h 15m | WN |
| Grand Rapids | GRR | USA | 1,377 km | 2h 16m | G4 |
| Des Moines | DSM | USA | 1,380 km | 2h 20m | G4 |
| Flint | FNT | USA | 1,407 km | 2h 20m | G4 |
| Philadelphia | PHL | USA | 1,461 km | 2h 34m | AA |
| Omaha | OMA | USA | 1,464 km | 2h 34m | G4 |
| New York | EWR | USA | 1,589 km | 2h 35m | G4 |
| New York | JFK | USA | 1,610 km | 2h 40m | B6 |
| New York | LGA | USA | 1,615 km | 2h 42m | DL |
| Minneapolis | MSP | USA | 1,699 km | 2h 55m | SY, DL |
| Boston | BOS | USA | 1,910 km | 2h 56m | G4, B6 |
| Denver | DEN | USA | 1,944 km | 3h 30m | WN, G4 |
| Las Vegas | LAS | USA | 2,724 km | 4h 20m | G4 |