Burlington International offers nonstop service to 36 destinations, served by 5 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| New York | LGA | USA | 414 km | 1h 32m | AA, DL |
| New York | EWR | USA | 428 km | 1h 42m | UA |
| New York | JFK | USA | 428 km | 1h 41m | DL |
| Philadelphia | PHL | USA | 538 km | 1h 36m | AA |
| Baltimore | BWI | USA | 655 km | 1h 50m | MX |
| Washington | DCA | USA | 702 km | 1h 54m | AA |
| Dulles | IAD | USA | 708 km | 1h 50m | UA |
| Detroit | DTW | USA | 863 km | 2h 9m | DL |
| Raleigh/Durham | RDU | USA | 1,067 km | 2h 19m | MX |
| Charlotte | CLT | USA | 1,222 km | 2h 30m | AA |
| Chicago | ORD | USA | 1,228 km | 2h 48m | AA, UA |
| Charleston | CHS | USA | 1,417 km | 2h 42m | MX |
| Atlanta | ATL | USA | 1,546 km | 2h 53m | DL |
| Minneapolis | MSP | USA | 1,586 km | 2h 56m | DL, SY |
| Orlando | MCO | USA | 1,921 km | 3h 37m | MX |
| Tampa | TPA | USA | 2,011 km | 3h 37m | MX |
| Fort Myers | RSW | USA | 2,135 km | 3h 49m | MX |
| Denver | DEN | USA | 2,637 km | 4h 29m | UA |