Thunder Bay offers nonstop service to 10 destinations, served by 6 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Sioux Lookout | YXL | Canada | 270 km | 1h 0m | JV, WP |
| Fort Hope | YFH | Canada | 368 km | 1h 0m | |
| Sault Ste. Marie | YAM | Canada | 419 km | 1h 15m | JV |
| Webequie | YWP | Canada | 528 km | 1h 30m | |
| Winnipeg | YWG | Canada | 601 km | 1h 35m | WS |
| Sudbury | YSB | Canada | 670 km | 1h 45m | JV |
| Toronto | YYZ | Canada | 913 km | 1h 47m | AC, F8, PD |
| Toronto | YTZ | Canada | 930 km | 2h 0m | PD |
| Ottawa | YOW | Canada | 1,092 km | 2h 13m | PD |
| Calgary | YYC | Canada | 1,797 km | 3h 5m | WS |