Scott Afb Midamerica offers nonstop service to 11 destinations, served by 1 airline.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Gulf Shores | GUF | USA | 936 km | 1h 46m | G4 |
| Fort Walton Beach | VPS | USA | 941 km | 1h 43m | G4 |
| Savannah | SAV | USA | 1,056 km | 1h 53m | G4 |
| Myrtle Beach | MYR | USA | 1,118 km | 1h 53m | G4 |
| Jacksonville | JAX | USA | 1,163 km | 2h 1m | G4 |
| Orlando | SFB | USA | 1,342 km | 2h 11m | G4 |
| Saint Petersburg | PIE | USA | 1,352 km | 2h 10m | G4 |
| Sarasota | SRQ | USA | 1,410 km | 2h 13m | G4 |
| Punta Gorda | PGD | USA | 1,482 km | 2h 26m | G4 |
| Fort Lauderdale | FLL | USA | 1,654 km | 2h 35m | G4 |
| Las Vegas | LAS | USA | 2,254 km | 3h 38m | G4 |