Tunis–Carthage International Airport offers nonstop service to 125 destinations, served by 29 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Palermo | PMO | Italy | 295 km | 1h 0m | UG |
| Djerba | DJE | Tunisia | 334 km | 0h 50m | TU, UG |
| Tozeur | TOE | Tunisia | 375 km | 1h 10m | UG |
| Malta | MLA | Malta | 399 km | 1h 10m | UG |
| Catania | CTA | Italy | 436 km | 1h 15m | UG |
| Mitiga, Tripoli | MJI | Libya | 519 km | 1h 10m | BM, LN, NJ, UZ, YL |
| Naples | NAP | Italy | 570 km | 1h 45m | UG |
| Rome | FCO | Italy | 576 km | 1h 25m | AZ, TU |
| Algiers | ALG | Algeria | 625 km | 1h 20m | AH, BJ, TU |
| Misurata | MRA | Libya | 670 km | 1h 20m | BM, NB, YL |
| Nice | NCE | France | 798 km | 1h 35m | BJ, TO, TU |
| Marseille | MRS | France | 846 km | 1h 40m | BJ, TO, TU |
| Bologna | BLQ | Italy | 857 km | 1h 45m | BJ, TU |
| Barcelona | BCN | Spain | 860 km | 1h 50m | BJ, TU, VY |
| Montpellier | MPL | France | 917 km | 1h 45m | TO |
| Venice | VCE | Italy | 977 km | 1h 45m | TU |
| Oran | ORN | Algeria | 981 km | 1h 45m | BJ, TU |
| Milan | MXP | Italy | 983 km | 1h 45m | BJ, TU |
| Benghazi | BEN | Libya | 1,062 km | 1h 45m | NB, UZ |
| Toulouse | TLS | France | 1,063 km | 1h 55m | BJ, TU |
| Lyon | LYS | France | 1,074 km | 1h 55m | BJ, TO, TU |
| Geneva | GVA | Switzerland | 1,096 km | 1h 55m | BJ, TU |
| Basel, Switzerland/Mulhouse | BSL | France | 1,214 km | 2h 10m | BJ |
| Athens | ATH | Greece | 1,220 km | 1h 55m | A3 |
| Madrid | MAD | Spain | 1,264 km | 2h 18m | TU, UX |
| Bordeaux | BOD | France | 1,276 km | 2h 13m | BJ, TU |
| Munich | MUC | Germany | 1,284 km | 2h 15m | BJ, LH, TU |
| Strasbourg | SXB | France | 1,316 km | 2h 15m | BJ, TU |
| Stuttgart | STR | Germany | 1,318 km | 2h 15m | EW |
| Vienna | VIE | Austria | 1,355 km | 2h 15m | TU |
| Luxembourg | LUX | Luxembourg | 1,456 km | 2h 20m | LG |
| Paris | ORY | France | 1,466 km | 2h 40m | TO, TU |
| Frankfurt | FRA | Germany | 1,472 km | 2h 35m | BJ, LH, TU |
| Paris | CDG | France | 1,485 km | 2h 35m | AF, BJ, TU |
| Nantes | NTE | France | 1,503 km | 2h 30m | BJ, TO |
| Rabat | RBA | Morocco | 1,569 km | 2h 40m | BJ |
| Cologne | CGN | Germany | 1,578 km | 2h 35m | EW |
| Brussels | BRU | Belgium | 1,626 km | 2h 45m | BJ, TU |
| Dusseldorf | DUS | Germany | 1,626 km | 2h 45m | BJ, EW, TU |
| Lille | LIL | France | 1,627 km | 2h 40m | BJ |
| Casablanca | CMN | Morocco | 1,665 km | 3h 15m | AT, BJ, TU |
| Istanbul | IST | Turkiye | 1,672 km | 2h 50m | BJ, TK, TU |
| Lisbon | LIS | Portugal | 1,713 km | 2h 50m | TU |
| Berlin | BER | Germany | 1,743 km | 2h 45m | BJ |
| London | LGW | United Kingdom | 1,790 km | 3h 5m | BJ, TU |
| London | LHR | United Kingdom | 1,830 km | 3h 5m | TU |
| Cairo | CAI | Egypt | 2,100 km | 3h 5m | BJ, MS, TU |
| Amman | AMM | Jordan | 2,432 km | 3h 45m | RJ |
| Niamey | NIM | Niger | 2,710 km | 4h 0m | TU |
| Ouagadougou | OUA | Burkina Faso | 2,955 km | 4h 20m | TU |
| Baghdad | BGW | Iraq | 3,112 km | 5h 0m | IA |
| Madinah | MED | Saudi Arabia | 3,119 km | 4h 5m | L6 |
| Bamako | BKO | Mali | 3,246 km | 4h 50m | TU |
| Jeddah | JED | Saudi Arabia | 3,256 km | 4h 15m | SV, TU |
| Nouakchott | NKC | Mauritania | 3,282 km | 4h 55m | L6, TU |
| Dakar | DSS | Senegal | 3,652 km | 5h 10m | TU |
| Abidjan | ABJ | Cote d'Ivoire | 3,784 km | 5h 20m | TU |
| Conakry | CKY | Guinea | 3,858 km | 5h 30m | TU |
| Doha | DOH | Qatar | 4,118 km | 5h 35m | QR |
| Abu Dhabi | AUH | United Arab Emirates | 4,432 km | 5h 45m | EY |
| Dubai | DXB | United Arab Emirates | 4,452 km | 6h 10m | EK |
| Montreal | YUL | Canada | 6,787 km | 8h 55m | TU |