Diori Hamani offers nonstop service to 13 destinations, served by 9 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Ouagadougou | OUA | Burkina Faso | 419 km | 1h 15m | 2J, ET, KP, HF |
| Maradi | MFQ | Niger | 535 km | 1h 40m | 6N |
| Agades | AJY | Niger | 734 km | 2h 0m | 6N |
| Lome | LFW | Togo | 814 km | 1h 35m | KP |
| Bamako | BKO | Mali | 1,103 km | 1h 55m | TK |
| Abidjan | ABJ | Cote d'Ivoire | 1,129 km | 2h 15m | HF, TU |
| Ndjamena | NDJ | Chad | 1,403 km | 2h 23m | TK, KP |
| Dakar | DSS | Senegal | 2,082 km | 3h 30m | KP |
| Casablanca | CMN | Morocco | 2,415 km | 3h 45m | AT |
| Algiers | ALG | Algeria | 2,574 km | 4h 5m | AH |
| Tunis | TUN | Tunisia | 2,710 km | 3h 45m | TU |
| Istanbul | IST | Turkiye | 4,014 km | 5h 50m | TK |
| Addis Ababa | ADD | Ethiopia | 4,025 km | 5h 45m | ET |