Ouagadougou offers nonstop service to 30 destinations, served by 11 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Bobo Dioulasso | BOY | Burkina Faso | 333 km | 0h 50m | 2J |
| Niamey | NIM | Niger | 419 km | 1h 0m | 2J, AH, ET, HF, KP |
| Bamako | BKO | Mali | 699 km | 1h 20m | 2J, HC |
| Lome | LFW | Togo | 748 km | 1h 40m | 2J, KP |
| Accra | ACC | Ghana | 760 km | 1h 25m | 2J, AW |
| Cotonou | COO | Benin | 789 km | 1h 30m | 2J |
| Abidjan | ABJ | Cote d'Ivoire | 829 km | 1h 30m | 2J, AH, HF, SN, TU |
| Conakry | CKY | Guinea | 1,358 km | 2h 0m | ET, TK |
| Dakar | DSS | Senegal | 1,703 km | 2h 50m | 2J |
| Casablanca | CMN | Morocco | 2,407 km | 3h 35m | AT |
| Algiers | ALG | Algeria | 2,737 km | 4h 30m | AH |
| Tunis | TUN | Tunisia | 2,955 km | 3h 55m | TU |
| Brussels | BRU | Belgium | 4,308 km | 6h 0m | SN |
| Istanbul | IST | Turkiye | 4,349 km | 6h 25m | TK |
| Addis Ababa | ADD | Ethiopia | 4,422 km | 6h 0m | ET |