Bamako Senou offers nonstop service to 25 destinations, served by 11 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Ouagadougou | OUA | Burkina Faso | 699 km | 1h 20m | 2J, HC |
| Conakry | CKY | Guinea | 701 km | 1h 30m | HF, KP, P4 |
| Abidjan | ABJ | Cote d'Ivoire | 918 km | 1h 40m | HF, L6, TU |
| Dakar | DSS | Senegal | 1,014 km | 1h 50m | 2J, ET, HC, KP |
| Nouakchott | NKC | Mauritania | 1,070 km | 1h 40m | L6 |
| Niamey | NIM | Niger | 1,103 km | 1h 58m | TK |
| Lome | LFW | Togo | 1,231 km | 2h 15m | KP |
| Cotonou | COO | Benin | 1,324 km | 2h 20m | SS |
| Lagos | LOS | Nigeria | 1,401 km | 2h 30m | P4 |
| Casablanca | CMN | Morocco | 2,306 km | 3h 25m | AT |
| Tunis | TUN | Tunisia | 3,246 km | 4h 30m | TU |
| Paris | ORY | France | 4,124 km | 6h 0m | SS |
| Addis Ababa | ADD | Ethiopia | 5,121 km | 6h 55m | ET |