Dar Es Salaam offers nonstop service to 86 destinations, served by 21 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Zanzibar | ZNZ | United Republic of Tanzania | 72 km | 0h 20m | CQ, FZ, PW, TC, UI, WB, WY |
| Mafia Island | MFA | United Republic of Tanzania | 126 km | 0h 30m | CQ, UI |
| Tanga | TGT | United Republic of Tanzania | 197 km | 0h 45m | UI |
| Mombasa | MBA | Kenya | 317 km | 0h 35m | OW |
| Dodoma | DOD | United Republic of Tanzania | 389 km | 1h 10m | TC |
| Iringa | IRI | United Republic of Tanzania | 391 km | 1h 15m | TC, UI |
| Mtwara | MYW | United Republic of Tanzania | 398 km | 1h 0m | PW, TC |
| Kilimanjaro | JRO | United Republic of Tanzania | 448 km | 1h 15m | PW, QR, TC |
| Arusha | ARK | United Republic of Tanzania | 477 km | 1h 15m | PW, TC |
| Songea | SGX | United Republic of Tanzania | 579 km | 1h 25m | TC |
| Nairobi | NBO | Kenya | 664 km | 1h 20m | KQ, TC, ZN |
| Mbeya | MBI | United Republic of Tanzania | 672 km | 1h 15m | TC |
| Moroni | HAH | Comoros | 682 km | 1h 15m | PW, TC |
| Pemba | POL | Mozambique | 691 km | 1h 10m | TM |
| Tabora | TBO | United Republic of Tanzania | 732 km | 2h 10m | TC |
| Kahama | KBH | United Republic of Tanzania | 795 km | 2h 0m | PW, UI |
| Musoma | MUZ | United Republic of Tanzania | 844 km | 1h 50m | TC |
| Sumbawanga | SUT | United Republic of Tanzania | 846 km | 2h 30m | TC |
| Mwanza | MWZ | United Republic of Tanzania | 851 km | 1h 30m | TC |
| Geita | GIT | United Republic of Tanzania | 897 km | 1h 30m | TC |
| Mpanda | NPY | United Republic of Tanzania | 899 km | 2h 0m | TC |
| Bukoba | BKZ | United Republic of Tanzania | 1,022 km | 2h 40m | TC |
| Entebbe | EBB | Uganda | 1,071 km | 1h 50m | TC, UR |
| Blantyre | BLZ | Malawi | 1,077 km | 2h 0m | ET |
| Kigoma | TKQ | United Republic of Tanzania | 1,078 km | 2h 20m | TC |
| Kigali | KGL | Rwanda | 1,143 km | 1h 55m | WB |
| Bujumbura | BJM | Burundi | 1,163 km | 2h 30m | TC |
| Ndola | NLA | Zambia | 1,351 km | 2h 20m | TC |
| Lubumbashi | FBM | The Democratic Republic of The Congo | 1,384 km | 2h 50m | TC |
| Lusaka | LUN | Zambia | 1,500 km | 2h 25m | TC, TK, ZN |
| Harare | HRE | Zimbabwe | 1,505 km | 2h 20m | TC, UM |
| Addis Ababa | ADD | Ethiopia | 1,754 km | 2h 40m | ET |
| Mahe Island | SEZ | Seychelles | 1,822 km | 2h 45m | TC |
| Victoria Falls | VFA | Zimbabwe | 1,908 km | 3h 0m | TC |
| Johannesburg | JNB | South Africa | 2,428 km | 3h 30m | 4Z, SA, TC |
| Kinshasa | FIH | The Democratic Republic of The Congo | 2,646 km | 3h 40m | TC |
| Doha | DOH | Qatar | 3,800 km | 5h 40m | QR |
| Muscat | MCT | Oman | 3,958 km | 5h 20m | TC, WY |
| Dubai | DXB | United Arab Emirates | 3,962 km | 5h 25m | EK, TC |
| Cairo | CAI | Egypt | 4,177 km | 5h 45m | MS |
| Lagos | LOS | Nigeria | 4,253 km | 5h 35m | TC |
| Mumbai | BOM | India | 4,677 km | 6h 0m | TC |
| Istanbul | IST | Turkiye | 5,435 km | 7h 40m | TK |
| Moscow | VKO | Russia | 6,926 km | 11h 15m | TC |
| Amsterdam | AMS | Netherlands | 7,326 km | 9h 20m | KL |
| Guangzhou | CAN | China | 8,712 km | 11h 0m | TC |