Kinshasa Ndjili International offers nonstop service to 56 destinations, served by 16 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Brazzaville | BZV | Congo | 25 km | 0h 38m | AF, AT, DT, HF, KP |
| Moanda | MNB | The Democratic Republic of The Congo | 382 km | 1h 25m | ET |
| Pointe Noire | PNR | Congo | 397 km | 1h 0m | J7 |
| Luanda | NBJ | Angola | 558 km | 1h 15m | BU, QR |
| Mbandaka | MDK | The Democratic Republic of The Congo | 581 km | 1h 50m | BU, ET |
| Kananga | KGA | The Democratic Republic of The Congo | 797 km | 1h 30m | BU, ET |
| Libreville | LBV | Gabon | 858 km | 1h 28m | J7 |
| Mbuji Mayi | MJM | The Democratic Republic of The Congo | 928 km | 1h 45m | BU, ET |
| Gemena | GMA | The Democratic Republic of The Congo | 970 km | 1h 50m | ET |
| Gbadolite | BDT | The Democratic Republic of The Congo | 1,136 km | 3h 10m | ET |
| Kindu | KND | The Democratic Republic of The Congo | 1,174 km | 2h 0m | BU, ET |
| Kisangani | FKI | The Democratic Republic of The Congo | 1,225 km | 2h 0m | BU, ET |
| Kolwezi | KWZ | The Democratic Republic of The Congo | 1,315 km | 2h 0m | BU |
| Kalemie | FMI | The Democratic Republic of The Congo | 1,539 km | 3h 30m | ET |
| Lubumbashi | FBM | The Democratic Republic of The Congo | 1,551 km | 2h 30m | BU, ET |
| Beni | BNC | The Democratic Republic of The Congo | 1,653 km | 4h 10m | ET |
| Entebbe | EBB | Uganda | 1,953 km | 3h 0m | UR |
| Lome | LFW | Togo | 1,962 km | 3h 10m | KP |
| Abidjan | ABJ | Cote d'Ivoire | 2,403 km | 3h 30m | HF |
| Nairobi | NBO | Kenya | 2,412 km | 3h 30m | KQ |
| Dar Es Salaam | DAR | United Republic of Tanzania | 2,646 km | 3h 40m | TC |
| Johannesburg | JNB | South Africa | 2,767 km | 4h 0m | ET, KP, SA |
| Addis Ababa | ADD | Ethiopia | 2,983 km | 4h 30m | ET |
| Cairo | CAI | Egypt | 4,180 km | 5h 50m | MS |
| Casablanca | CMN | Morocco | 4,831 km | 6h 45m | AT |
| Abu Dhabi | AUH | United Arab Emirates | 5,308 km | 7h 35m | EY |
| Paris | CDG | France | 6,045 km | 8h 20m | AF |
| Brussels | BRU | Belgium | 6,214 km | 8h 3m | ET, SN |