Lubumbashi International offers nonstop service to 24 destinations, served by 7 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Ndola | NLA | Zambia | 185 km | 0h 45m | KQ, TC |
| Kolwezi | KWZ | The Democratic Republic of The Congo | 238 km | 0h 45m | BU, ET |
| Lusaka | LUN | Zambia | 425 km | 1h 15m | TC |
| Kalemie | FMI | The Democratic Republic of The Congo | 659 km | 2h 0m | BU, ET |
| Mbuji Mayi | MJM | The Democratic Republic of The Congo | 738 km | 1h 48m | BU, ET |
| Kananga | KGA | The Democratic Republic of The Congo | 838 km | 2h 20m | ET |
| Dar Es Salaam | DAR | United Republic of Tanzania | 1,384 km | 2h 20m | TC |
| Nairobi | NBO | Kenya | 1,538 km | 2h 30m | KQ |
| Kinshasa | FIH | The Democratic Republic of The Congo | 1,551 km | 2h 30m | BU, ET |
| Johannesburg | JNB | South Africa | 1,612 km | 2h 40m | 4Z, SA |
| Addis Ababa | ADD | Ethiopia | 2,594 km | 3h 55m | ET |
| Abu Dhabi | AUH | United Arab Emirates | 4,956 km | 6h 35m | EY |