Chileka International offers nonstop service to 10 destinations, served by 2 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Lilongwe | LLW | Malawi | 245 km | 0h 30m | ET |
| Beira | BEW | Mozambique | 456 km | 1h 13m | ET |
| Nacala | MNC | Mozambique | 630 km | 1h 5m | ET |
| Dar Es Salaam | DAR | United Republic of Tanzania | 1,077 km | 2h 0m | ET |
| Johannesburg | JNB | South Africa | 1,352 km | 2h 25m | 4Z, ET |
| Addis Ababa | ADD | Ethiopia | 2,759 km | 4h 5m | ET |