Yining Airport offers nonstop service to 79 destinations, served by 14 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Kuqa | KCA | China | 282 km | 0h 50m | EU, G5 |
| Aksu | AKU | China | 310 km | 0h 55m | EU, G5 |
| Karamay | KRY | China | 336 km | 0h 55m | CA, G5 |
| Tacheng | TCG | China | 340 km | 1h 0m | EU |
| Almaty | ALA | Kazakhstan | 352 km | 1h 20m | FS |
| Luntai | LTJ | China | 356 km | 0h 55m | G5 |
| Shihezi | SHF | China | 366 km | 0h 55m | EU |
| Alaer | ACF | China | 390 km | 1h 5m | G5 |
| Korla | KRL | China | 471 km | 1h 0m | G5 |
| Tumushuke | TWC | China | 483 km | 1h 15m | EU, G5 |
| Urumqi | URC | China | 493 km | 1h 20m | CZ, GS, MU |
| Turpan | TLQ | China | 634 km | 1h 20m | EU |
| Qitai | JBK | China | 658 km | 1h 15m | EU |
| Kashi | KHG | China | 660 km | 1h 35m | EU, G5 |
| Altay | AAT | China | 672 km | 1h 15m | EU, G5 |
| Fuyun | FYN | China | 716 km | 1h 25m | EU |
| Shache | QSZ | China | 728 km | 1h 30m | EU |
| Hotan | HTN | China | 777 km | 1h 40m | EU |
| Yutian | YTW | China | 794 km | 1h 45m | EU |
| Hami | HMI | China | 984 km | 1h 53m | EU, G5 |
| Astana | NQZ | Kazakhstan | 1,080 km | 2h 30m | FS |
| Lanzhou | LHW | China | 2,060 km | 3h 0m | 9C, QW |
| Yinchuan | INC | China | 2,184 km | 3h 15m | JD |
| Chengdu | CTU | China | 2,481 km | 4h 0m | 3U, EU |
| Chengdu | TFU | China | 2,536 km | 4h 0m | 3U, 9C, CA, CZ, EU, MU |
| Xian | XIY | China | 2,578 km | 3h 45m | 9C, MU |
| Chongqing | CKG | China | 2,737 km | 4h 10m | OQ |
| Shijiazhuang | SJW | China | 2,851 km | 4h 30m | 9C |
| Beijing | PEK | China | 2,929 km | 4h 10m | CA |
| Beijing | PKX | China | 2,937 km | 4h 15m | CZ |
| Zhengzhou | CGO | China | 2,971 km | 4h 15m | 9C, CZ, UQ |
| Jinan | TNA | China | 3,118 km | 4h 45m | EU |
| Wuhan | WUH | China | 3,230 km | 4h 45m | EU |
| Changsha | CSX | China | 3,330 km | 5h 0m | EU |
| Hefei | HFE | China | 3,368 km | 4h 50m | 9C |
| Nanjing | NKG | China | 3,533 km | 4h 50m | CZ, MU |
| Shanghai | SHA | China | 3,762 km | 4h 50m | MU |
| Shenzhen | SZX | China | 3,797 km | 6h 10m | CZ |
| Shanghai | PVG | China | 3,802 km | 5h 18m | HO, MU |