Hami Airport offers nonstop service to 23 destinations, served by 10 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Dunhuang | DNH | China | 319 km | 0h 50m | G5 |
| Qitai | JBK | China | 341 km | 0h 55m | G5 |
| Urumqi | URC | China | 493 km | 1h 0m | GS, G5 |
| Korla | KRL | China | 617 km | 1h 35m | G5 |
| Shihezi | SHF | China | 624 km | 1h 28m | G5 |
| Altay | AAT | China | 680 km | 1h 25m | G5, EU |
| Karamay | KRY | China | 743 km | 1h 40m | G5 |
| Kuqa | KCA | China | 869 km | 1h 55m | G5 |
| Tacheng | TCG | China | 898 km | 1h 45m | G5 |
| Yining | YIN | China | 984 km | 2h 5m | G5, EU |
| Aksu | AKU | China | 1,100 km | 2h 5m | EU |
| Lanzhou | LHW | China | 1,126 km | 2h 8m | G5 |
| Yinchuan | INC | China | 1,208 km | 2h 13m | G5 |
| Hotan | HTN | China | 1,325 km | 2h 48m | EU |
| Yulin | UYN | China | 1,456 km | 2h 20m | G5 |
| Kashi | KHG | China | 1,503 km | 2h 33m | EU |
| Xian | XIY | China | 1,629 km | 2h 35m | GS, Y8 |
| Chengdu | TFU | China | 1,707 km | 2h 55m | CA |
| Luoyang | LYA | China | 1,874 km | 3h 8m | Y8 |
| Beijing | PEK | China | 1,953 km | 3h 0m | CA |
| Beijing | PKX | China | 1,958 km | 3h 0m | KN |
| Zhengzhou | CGO | China | 1,998 km | 3h 15m | CZ, UQ, FU, PN |
| Jinan | TNA | China | 2,134 km | 3h 35m | EU |