Shache Airport offers nonstop service to 16 destinations, served by 4 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Kashi | KHG | China | 169 km | 0h 48m | G5 |
| Tumushuke | TWC | China | 262 km | 0h 40m | G5 |
| Hotan | HTN | China | 282 km | 1h 0m | G5 |
| Aksu | AKU | China | 434 km | 1h 0m | G5 |
| Alaer | ACF | China | 436 km | 1h 0m | EU |
| Kuqa | KCA | China | 636 km | 1h 10m | EU, G5 |
| Yining | YIN | China | 728 km | 1h 30m | EU, G5 |
| Qiemo | IQM | China | 742 km | 1h 30m | EU |
| Bole | BPL | China | 857 km | 1h 40m | EU |
| Korla | KRL | China | 861 km | 1h 35m | G5 |
| Karamay | KRY | China | 1,043 km | 1h 53m | EU |
| Urumqi | URC | China | 1,076 km | 1h 50m | CZ |
| Turpan | TLQ | China | 1,145 km | 1h 55m | EU |
| Altay | AAT | China | 1,384 km | 2h 20m | EU |
| Lanzhou | LHW | China | 2,352 km | 3h 10m | EU |
| Yan'an | ENY | China | 2,862 km | 4h 25m | A6 |