Norman Manley International Airport offers nonstop service to 37 destinations, served by 15 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Santiago | SCU | Cuba | 246 km | 0h 55m | JY |
| Grand Cayman Island | GCM | Cayman Islands | 505 km | 1h 15m | KX |
| Cap Haitien | CAP | Haiti | 523 km | 1h 0m | S6 |
| Providenciales | PLS | Turks and Caicos Islands | 636 km | 1h 45m | 9Q, JY |
| Santo Domingo | SDQ | Dominican Republic | 754 km | 1h 34m | 5L, DM |
| Nassau | NAS | Bahamas | 790 km | 1h 30m | BW |
| Punta Cana | PUJ | Dominican Republic | 893 km | 1h 48m | DM |
| Miami | MIA | USA | 942 km | 2h 2m | AA |
| Fort Lauderdale | FLL | USA | 965 km | 1h 53m | B6 |
| Panama City | PTY | Panama | 1,020 km | 2h 2m | CM |
| Sint Maarten | SXM | Sint Maarten | 1,448 km | 2h 20m | BW |
| Antigua | ANU | Antigua and Barbuda | 1,594 km | 2h 25m | 5L, BW |
| Port Of Spain | POS | Trinidad and Tobago | 1,852 km | 2h 45m | BW |
| Atlanta | ATL | USA | 1,900 km | 3h 10m | DL |
| Bridgetown | BGI | Barbados | 1,931 km | 2h 40m | BW, JY |
| New York | JFK | USA | 2,533 km | 3h 53m | B6, BW |
| Toronto | YYZ | Canada | 2,866 km | 4h 25m | AC, BW, F8, WS |
| London | LGW | United Kingdom | 7,545 km | 8h 55m | BA |