General Ignacio P Garcia International offers nonstop service to 14 destinations, served by 5 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Phoenix | PHX | USA | 490 km | 1h 21m | AA |
| Chihuahua | CUU | Mexico | 497 km | 1h 5m | YQ |
| Ciudad Juarez | CJS | Mexico | 525 km | 1h 35m | YQ |
| La Paz | LAP | Mexico | 559 km | 1h 10m | YQ |
| Mexicali | MXL | Mexico | 561 km | 1h 12m | Y4 |
| Culiacan | CUL | Mexico | 596 km | 1h 15m | YQ |
| San Jose Cabo | SJD | Mexico | 670 km | 1h 27m | VB |
| Tijuana | TIJ | Mexico | 683 km | 1h 26m | Y4 |
| Durango | DGO | Mexico | 851 km | 1h 40m | YQ |
| Monterrey | MTY | Mexico | 1,141 km | 1h 58m | VB |
| Guadalajara | GDL | Mexico | 1,229 km | 2h 5m | VB, Y4 |
| Queretaro | QRO | Mexico | 1,442 km | 2h 15m | YQ |
| Mexico City | NLU | Mexico | 1,597 km | 2h 26m | VB |
| Mexico City | MEX | Mexico | 1,617 km | 2h 40m | AM, Y4, VB |