Abraham Gonzalez International offers nonstop service to 22 destinations, served by 4 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Hermosillo | HMO | Mexico | 525 km | 1h 5m | YQ |
| Torreon | TRC | Mexico | 735 km | 1h 20m | YQ |
| Monterrey | MTY | Mexico | 895 km | 1h 40m | VB |
| Mazatlan | MZT | Mexico | 938 km | 1h 44m | VB |
| Tijuana | TIJ | Mexico | 999 km | 1h 54m | Y4 |
| Puerto Vallarta | PVR | Mexico | 1,219 km | 2h 24m | VB |
| Guadalajara | GDL | Mexico | 1,270 km | 2h 13m | VB, Y4 |
| Leon/Guanajuato | BJX | Mexico | 1,278 km | 2h 3m | VB |
| Mexico City | NLU | Mexico | 1,511 km | 2h 24m | VB |
| Mexico City | MEX | Mexico | 1,539 km | 2h 41m | AM, VB, Y4 |
| Cancun | CUN | Mexico | 2,272 km | 3h 21m | VB |