Culiacan International offers nonstop service to 11 destinations, served by 4 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| San Jose Cabo | SJD | Mexico | 289 km | 0h 55m | VB, Y4 |
| La Paz | LAP | Mexico | 303 km | 0h 55m | VB |
| Chihuahua | CUU | Mexico | 461 km | 1h 0m | YQ |
| Hermosillo | HMO | Mexico | 596 km | 1h 15m | YQ |
| Guadalajara | GDL | Mexico | 635 km | 1h 23m | Y4 |
| Monterrey | MTY | Mexico | 749 km | 1h 25m | VB, Y4 |
| Mexico City | NLU | Mexico | 1,032 km | 1h 50m | VB |
| Mexico City | MEX | Mexico | 1,047 km | 1h 58m | AM, Y4 |
| Phoenix | PHX | USA | 1,056 km | 1h 53m | Y4 |
| Mexicali | MXL | Mexico | 1,155 km | 1h 58m | Y4 |
| Tijuana | TIJ | Mexico | 1,266 km | 2h 9m | VB, Y4 |