Phuket International Airport offers nonstop service to 149 destinations, served by 64 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Koh Samui | USM | Thailand | 250 km | 0h 55m | PG |
| Hat Yai | HDY | Thailand | 264 km | 1h 0m | PG |
| Penang | PEN | Malaysia | 379 km | 1h 0m | AK, FY, QR |
| Utapao | UTP | Thailand | 586 km | 1h 40m | PG |
| Bangkok | BKK | Thailand | 673 km | 1h 35m | FD, PG, TG, VZ |
| Bangkok | DMK | Thailand | 689 km | 1h 25m | DD, FD, SL |
| Kuala Lumpur | KUL | Malaysia | 703 km | 1h 35m | AK, MH, OD |
| Siem Reap | SAI | Cambodia | 870 km | 1h 35m | FD |
| Ho Chi Minh City | SGN | Viet Nam | 965 km | 2h 0m | VJ, VN |
| Singapore | SIN | Singapore | 976 km | 2h 10m | SL, SQ, TR |
| Yangon | RGN | Myanmar | 1,000 km | 1h 45m | 8M |
| Khon Kaen | KKC | Thailand | 1,044 km | 1h 45m | FD |
| Udon Thani | UTH | Thailand | 1,135 km | 1h 55m | FD |
| Chiang Mai | CNX | Thailand | 1,181 km | 2h 5m | FD, VZ |
| Nha Trang | CXR | Viet Nam | 1,271 km | 2h 0m | B2 |
| Chiang Rai | CEI | Thailand | 1,321 km | 2h 5m | VZ |
| Kolkata | CCU | India | 1,924 km | 3h 0m | 6E |
| Kunming | KMG | China | 1,943 km | 3h 15m | MU |
| Hong Kong | HKG | Hong Kong SAR | 2,296 km | 3h 50m | CX, HX, UO |
| Shenzhen | SZX | China | 2,310 km | 4h 0m | 9C |
| Bengaluru | BLR | India | 2,321 km | 3h 50m | 6E, IX |
| Guangzhou | CAN | China | 2,328 km | 3h 55m | 9C, CZ |
| Hyderabad | HYD | India | 2,380 km | 4h 5m | IX |
| Chengdu | TFU | China | 2,540 km | 3h 45m | 3U, 9C, CA |
| Denpasar | DPS | Indonesia | 2,640 km | 4h 0m | 8B, QZ |
| Mumbai | BOM | India | 3,003 km | 4h 40m | 6E, SG, VZ |
| Taipei | TPE | Taiwan | 3,074 km | 4h 15m | IT |
| Xian | XIY | China | 3,106 km | 4h 30m | 9H |
| Delhi | DEL | India | 3,173 km | 4h 50m | 6E, AI, SG |
| Hangzhou | HGH | China | 3,364 km | 4h 45m | CA |
| Shanghai | PVG | China | 3,529 km | 5h 20m | 9C, FM, HO |
| Beijing | PEK | China | 3,980 km | 5h 40m | CA, HU |
| Seoul | ICN | Republic of Korea | 4,313 km | 6h 10m | KE, OZ |
| Almaty | ALA | Kazakhstan | 4,421 km | 7h 15m | KC |
| Ulaanbaatar | UBN | Mongolia | 4,456 km | 6h 30m | OM |
| Muscat | MCT | Oman | 4,595 km | 6h 15m | WY |
| Tashkent | TAS | Uzbekistan | 4,656 km | 6h 50m | C6, HY |
| Perth | PER | Australia | 4,812 km | 6h 23m | JQ |
| Sharjah | SHJ | United Arab Emirates | 4,915 km | 6h 25m | G9 |
| Dubai | DXB | United Arab Emirates | 4,928 km | 6h 5m | EK |
| Irkutsk | IKT | Russia | 4,928 km | 7h 0m | S7, SU |
| Abu Dhabi | AUH | United Arab Emirates | 4,976 km | 6h 23m | EY |
| Vladivostok | VVO | Russia | 5,110 km | 7h 5m | SU |
| Doha | DOH | Qatar | 5,296 km | 6h 50m | QR |
| Krasnojarsk | KJA | Russia | 5,356 km | 7h 45m | SU |
| Astana | NQZ | Kazakhstan | 5,360 km | 8h 45m | KC |
| Novosibirsk | OVB | Russia | 5,383 km | 8h 35m | S7, SU |
| Khabarovsk | KHV | Russia | 5,656 km | 7h 50m | SU |
| Tehran | IKA | Iran | 5,661 km | 7h 35m | W5 |
| Kuwait | KWI | Kuwait | 5,747 km | 8h 20m | KU |
| Riyadh | RUH | Saudi Arabia | 5,775 km | 7h 35m | SV |
| Yekaterinburg | SVX | Russia | 6,300 km | 9h 20m | SU |
| Jeddah | JED | Saudi Arabia | 6,501 km | 8h 38m | SV |
| Melbourne | MEL | Australia | 7,001 km | 8h 30m | JQ |
| Tel Aviv-Yafo | TLV | Israel | 7,037 km | 10h 40m | IZ, LY |
| Sydney | SYD | Australia | 7,258 km | 8h 45m | JQ |
| Moscow | SVO | Russia | 7,477 km | 10h 8m | SU |
| Istanbul | IST | Turkiye | 7,713 km | 10h 55m | TK |
| Minsk | MSQ | Belarus | 7,994 km | 10h 55m | B2 |
| Saint Petersburg | LED | Russia | 8,010 km | 11h 20m | SU |
| Sofia | SOF | Bulgaria | 8,168 km | 10h 25m | G2 |
| Helsinki | HEL | Finland | 8,311 km | 12h 45m | AY |
| Warsaw | WAW | Poland | 8,436 km | 11h 30m | NO |
| Budapest | BUD | Hungary | 8,525 km | 12h 10m | NO |
| Stockholm | ARN | Sweden | 8,691 km | 12h 20m | N0 |
| Brno | BRQ | Czech Republic | 8,721 km | 11h 50m | NO |
| Prague | PRG | Czech Republic | 8,897 km | 12h 5m | NO |
| Copenhagen | CPH | Denmark | 8,995 km | 12h 40m | SK |
| Oslo | OSL | Norway | 9,074 km | 13h 15m | N0 |
| Frankfurt | FRA | Germany | 9,304 km | 12h 30m | DE |
| Zurich | ZRH | Switzerland | 9,331 km | 12h 40m | WK |
| Milan | MXP | Italy | 9,339 km | 12h 15m | NO |
| Paris | CDG | France | 9,750 km | 13h 15m | AF |
| London | LGW | United Kingdom | 9,898 km | 12h 50m | |
| London | LHR | United Kingdom | 9,910 km | 13h 38m | VS |