Imam Khomeini offers nonstop service to 71 destinations, served by 14 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Sulaimaniyah | ISU | Iraq | 531 km | 1h 50m | W5 |
| Baku | GYD | Azerbaijan | 569 km | 1h 30m | B9 |
| Erbil | EBL | Iraq | 656 km | 1h 33m | W5 |
| Baghdad | BGW | Iraq | 680 km | 1h 30m | B9, IR, IS, W5 |
| Al-Najaf | NJF | Iraq | 731 km | 1h 30m | IR, IS |
| Kuwait | KWI | Kuwait | 746 km | 1h 50m | KU |
| Yerevan | EVN | Armenia | 794 km | 1h 30m | B9 |
| Tbilisi | TBS | Georgia | 880 km | 1h 45m | B9, IS |
| Batumi | BUS | Georgia | 1,079 km | 1h 45m | IS |
| Doha | DOH | Qatar | 1,125 km | 2h 10m | QR |
| Dubai | DXB | United Arab Emirates | 1,195 km | 2h 15m | B9, IS, QB |
| Mazar-I-Sharif | MZR | Afghanistan | 1,451 km | 2h 30m | W5 |
| Muscat | MCT | Oman | 1,479 km | 2h 40m | IS, OV, QB, W5 |
| Kabul | KBL | Afghanistan | 1,649 km | 2h 30m | B9, W5 |
| Ankara | ESB | Turkiye | 1,679 km | 2h 45m | W5 |
| Islamabad | ISB | Pakistan | 1,997 km | 3h 30m | B9 |
| Istanbul | SAW | Turkiye | 2,003 km | 3h 35m | VF |
| Istanbul | IST | Turkiye | 2,057 km | 3h 35m | B9, IR, IS, QB, TK, W5 |
| Izmir | ADB | Turkiye | 2,158 km | 3h 30m | B9 |
| Lahore | LHE | Pakistan | 2,198 km | 3h 25m | W5 |
| Moscow | VKO | Russia | 2,481 km | 4h 15m | |
| Moscow | SVO | Russia | 2,512 km | 4h 10m | SU, W5 |
| Delhi | DEL | India | 2,558 km | 3h 40m | W5 |
| Saint Petersburg | LED | Russia | 3,103 km | 4h 55m | W5 |
| Vienna | VIE | Austria | 3,168 km | 4h 45m | OS |
| Urumqi | URC | China | 3,227 km | 4h 30m | CZ |
| Frankfurt | FRA | Germany | 3,782 km | 5h 30m | LH |
| Bangkok | BKK | Thailand | 5,499 km | 6h 35m | W5 |
| Hanoi | HAN | Viet Nam | 5,513 km | 7h 40m | W5 |
| Beijing | PEK | China | 5,659 km | 6h 50m | W5 |
| Phuket | HKT | Thailand | 5,661 km | 6h 40m | W5 |
| Beijing | PKX | China | 5,663 km | 7h 20m | CZ |
| Guangzhou | CAN | China | 6,079 km | 7h 5m | W5 |
| Ho Chi Minh City | SGN | Viet Nam | 6,208 km | 7h 45m | W5 |
| Kuala Lumpur | KUL | Malaysia | 6,333 km | 8h 0m | B9 |