Imam Khomeini offers nonstop service to 41 destinations, served by 23 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Sulaimaniyah | ISU | Iraq | 531 km | 1h 25m | W5 |
| Tabriz | TBZ | Iran | 531 km | 1h 10m | QB |
| Baku | GYD | Azerbaijan | 569 km | 1h 28m | J2, IR, B9 |
| Erbil | EBL | Iraq | 656 km | 1h 35m | W5 |
| Baghdad | BGW | Iraq | 680 km | 1h 40m | IR, W5, B9, IS |
| Al-Najaf | NJF | Iraq | 731 km | 0h 30m | EP, IR, QB, W5 |
| Kuwait | KWI | Kuwait | 746 km | 1h 40m | KU, J9 |
| Yerevan | EVN | Armenia | 794 km | 1h 30m | B9, 6A, IS |
| Tbilisi | TBS | Georgia | 880 km | 0h 45m | QB, EP, IS, B9 |
| Batumi | BUS | Georgia | 1,079 km | 2h 5m | |
| Doha | DOH | Qatar | 1,125 km | 2h 10m | QR |
| Sharjah | SHJ | United Arab Emirates | 1,194 km | 2h 5m | G9 |
| Dubai | DXB | United Arab Emirates | 1,195 km | 2h 15m | FZ, QB, W5, B9 |
| Damascus | DAM | Syrian Arab Republic | 1,362 km | 2h 45m | |
| Muscat | MCT | Oman | 1,479 km | 2h 30m | OV, IS |
| Dushanbe | DYU | Tajikistan | 1,608 km | 2h 25m | SZ, DW |
| Kabul | KBL | Afghanistan | 1,649 km | 2h 35m | W5, B9 |
| Ankara | ESB | Turkiye | 1,679 km | 2h 50m | W5, PC, VF |
| Denizli | DNZ | Turkiye | 1,933 km | 2h 40m | QB |
| Islamabad | ISB | Pakistan | 1,997 km | 3h 15m | B9, W5 |
| Istanbul | SAW | Turkiye | 2,003 km | 3h 30m | PC, VF |
| Dalaman | DLM | Turkiye | 2,015 km | 3h 30m | |
| Istanbul | IST | Turkiye | 2,057 km | 3h 35m | IR, QB, TK, W5, B9, IS |
| Izmir | ADB | Turkiye | 2,158 km | 3h 15m | B9 |
| Lahore | LHE | Pakistan | 2,198 km | 3h 20m | W5 |
| Moscow | VKO | Russia | 2,481 km | 4h 0m | |
| Moscow | SVO | Russia | 2,512 km | 4h 10m | SU, W5 |
| Delhi | DEL | India | 2,558 km | 4h 0m | W5 |
| Mumbai | BOM | India | 2,797 km | 4h 30m | IR |
| Saint Petersburg | LED | Russia | 3,103 km | 4h 58m | W5 |
| Vienna | VIE | Austria | 3,168 km | 4h 45m | OS |
| Urumqi | URC | China | 3,227 km | 4h 30m | CZ |
| Frankfurt | FRA | Germany | 3,782 km | 5h 30m | LH |
| Bangkok | BKK | Thailand | 5,499 km | 7h 5m | W5 |
| Beijing | PEK | China | 5,659 km | 6h 58m | W5 |
| Phuket | HKT | Thailand | 5,661 km | 7h 10m | W5 |
| Beijing | PKX | China | 5,663 km | 7h 20m | CZ |
| Guangzhou | CAN | China | 6,079 km | 7h 45m | W5 |
| Shenzhen | SZX | China | 6,164 km | 7h 30m | W5 |
| Kuala Lumpur | KUL | Malaysia | 6,333 km | 8h 0m | B9 |
| Shanghai | PVG | China | 6,456 km | 8h 15m | W5 |