Samui offers nonstop service to 9 destinations, served by 2 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Krabi | KBV | Thailand | 200 km | 0h 50m | PG |
| Phuket | HKT | Thailand | 250 km | 1h 0m | PG |
| Utapao | UTP | Thailand | 361 km | 1h 10m | PG |
| Bangkok | BKK | Thailand | 464 km | 1h 15m | PG |
| Bangkok | DMK | Thailand | 486 km | 1h 33m | PG |
| Singapore | SIN | Singapore | 1,004 km | 1h 55m | PG, TR |
| Chiang Mai | CNX | Thailand | 1,026 km | 1h 50m | PG |
| Hong Kong | HKG | Hong Kong SAR | 2,046 km | 3h 15m | PG |
| Chengdu | TFU | China | 2,343 km | 3h 30m | PG |