Long Island Mac Arthur offers nonstop service to 32 destinations, served by 6 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Boston | BOS | USA | 246 km | 1h 25m | 9K |
| Baltimore | BWI | USA | 353 km | 1h 20m | WN |
| Norfolk | ORF | USA | 509 km | 1h 25m | MX |
| Richmond | RIC | USA | 515 km | 1h 26m | MX |
| Raleigh/Durham | RDU | USA | 738 km | 1h 44m | MX |
| Wilmington | ILM | USA | 839 km | 1h 58m | MX |
| Concord | USA | USA | 897 km | 2h 4m | XP |
| Myrtle Beach | MYR | USA | 942 km | 2h 0m | MX |
| Charleston | CHS | USA | 1,072 km | 2h 12m | MX |
| Orlando | MCO | USA | 1,562 km | 2h 55m | B6, F9, WN |
| Vero Beach | VRB | USA | 1,604 km | 3h 4m | MX |
| Tampa | TPA | USA | 1,662 km | 3h 5m | B6, F9, MX, WN |
| West Palm Beach | DJT | USA | 1,692 km | 3h 0m | B6, WN |
| Sarasota | SRQ | USA | 1,721 km | 3h 15m | MX |
| Fort Lauderdale | FLL | USA | 1,757 km | 3h 5m | B6, WN |
| Fort Myers | RSW | USA | 1,771 km | 3h 16m | B6, MX |