Aniak Airport offers nonstop service to 22 destinations, served by 0 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Chuathbaluk | CHU | USA | 15 km | 0h 5m | |
| Kalskag | KLG | USA | 43 km | 0h 13m | |
| Holy Cross | HCR | USA | 69 km | 0h 25m | |
| Crooked Creek | CKD | USA | 82 km | 0h 25m | |
| Russian Mission | RSH | USA | 97 km | 0h 21m | |
| Anvik | ANV | USA | 124 km | 0h 37m | |
| Shageluk | SHX | USA | 124 km | 0h 40m | |
| Sleetmute | SLQ | USA | 126 km | 0h 38m | |
| Grayling | KGX | USA | 149 km | 0h 36m | |
| Bethel | BET | USA | 151 km | 0h 45m | |
| Stony River | SRV | USA | 157 km | 0h 47m | |
| Emmonak | EMK | USA | 291 km | 0h 25m | |
| Anchorage | ANC | USA | 511 km | 1h 15m |