Dr Antonio Agostinho Neto Airport offers nonstop service to 70 destinations, served by 13 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Soyo | SZA | Angola | 344 km | 1h 0m | DT |
| Catumbela | CBT | Angola | 379 km | 1h 15m | DT |
| Cabinda | CAB | Angola | 409 km | 1h 15m | DT |
| Huambo | NOV | Angola | 483 km | 1h 35m | DT |
| Pointe Noire | PNR | Congo | 501 km | 1h 20m | KP |
| Kuito | SVP | Angola | 529 km | 1h 35m | DT |
| Kinshasa | FIH | The Democratic Republic of The Congo | 558 km | 1h 28m | BU, DT, TK |
| Lubango | SDD | Angola | 649 km | 1h 40m | DT |
| Namibe | MSZ | Angola | 702 km | 1h 45m | DT |
| Luena | LUO | Angola | 762 km | 1h 50m | DT |
| Menongue | SPP | Angola | 770 km | 1h 50m | DT |
| Saurimo | VHC | Angola | 778 km | 1h 45m | DT |
| Dundo | DUE | Angola | 826 km | 1h 55m | DT |
| Ongiva | VPE | Angola | 916 km | 2h 10m | DT |
| Sao Tome Island | TMS | Sao Tome and Principe | 1,284 km | 2h 15m | DT |
| Windhoek | WDH | Namibia | 1,546 km | 2h 30m | DT |
| Lagos | LOS | Nigeria | 2,064 km | 3h 15m | DT |
| Lome | LFW | Togo | 2,163 km | 3h 30m | KP |
| Johannesburg | JNB | South Africa | 2,450 km | 3h 45m | 4Z, AH, DT |
| Abidjan | ABJ | Cote d'Ivoire | 2,498 km | 3h 40m | DT |
| Nairobi | NBO | Kenya | 2,732 km | 4h 0m | DT |
| Maputo | MPM | Mozambique | 2,747 km | 4h 5m | DT |
| Cape Town | CPT | South Africa | 2,808 km | 4h 0m | DT |
| Addis Ababa | ADD | Ethiopia | 3,441 km | 4h 45m | ET |
| Algiers | ALG | Algeria | 5,176 km | 6h 35m | AH |
| Casablanca | CMN | Morocco | 5,198 km | 7h 5m | AT |
| Doha | DOH | Qatar | 5,610 km | 7h 55m | QR |
| Istanbul | IST | Turkiye | 5,785 km | 8h 15m | TK |
| Lisbon | LIS | Portugal | 5,789 km | 7h 55m | DT, TP |
| Dubai | DXB | United Arab Emirates | 5,915 km | 7h 50m | EK |
| Porto | OPO | Portugal | 6,013 km | 8h 20m | DT, TP |
| Paris | CDG | France | 6,519 km | 9h 23m | AF |
| Sao Paulo | GRU | Brazil | 6,561 km | 8h 30m | DT |
| Frankfurt | FRA | Germany | 6,564 km | 8h 35m | LH |
| Havana | HAV | Cuba | 11,005 km | 14h 40m | DT |
| Guangzhou | CAN | China | 11,406 km | 13h 45m | DT |