Antananarivo Ivato offers nonstop service to 18 destinations, served by 11 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Tamatave | TMM | Madagascar | 216 km | 0h 50m | MD |
| Sainte Marie | SMS | Madagascar | 312 km | 1h 5m | MD |
| Majunga | MJN | Madagascar | 366 km | 1h 10m | MD |
| Morondava | MOQ | Madagascar | 369 km | 1h 10m | MD |
| Maroantsetra | WMN | Madagascar | 440 km | 1h 20m | MD |
| Sambava | SVB | Madagascar | 577 km | 1h 35m | MD |
| Nossi-be | NOS | Madagascar | 613 km | 1h 45m | MD |
| Toliara | TLE | Madagascar | 640 km | 1h 45m | MD |
| Fort Dauphin | FTU | Madagascar | 692 km | 1h 55m | MD |
| Dzaoudzi | DZA | Mayotte | 703 km | 1h 50m | ZD |
| Antsiranana | DIE | Madagascar | 740 km | 2h 0m | MD |
| Saint Denis de la Reunion | RUN | Reunion | 872 km | 1h 35m | SS, UU |
| Mauritius | MRU | Mauritius | 1,085 km | 1h 50m | MK, TK |
| Mahe Island | SEZ | Seychelles | 1,790 km | 2h 45m | EK |
| Johannesburg | JNB | South Africa | 2,136 km | 3h 20m | 4Z |
| Nairobi | NBO | Kenya | 2,250 km | 3h 20m | KQ |
| Addis Ababa | ADD | Ethiopia | 3,217 km | 4h 40m | ET |
| Paris | CDG | France | 8,724 km | 11h 25m | AF |