Malabo offers nonstop service to 25 destinations, served by 7 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Douala | DLA | Cameroon | 114 km | 0h 45m | AF, C2, ET, J7, KP |
| Bata | BSG | Equatorial Guinea | 237 km | 0h 50m | C2 |
| Port Harcourt | PHC | Nigeria | 239 km | 0h 45m | |
| Yaounde | NSI | Cameroon | 314 km | 1h 0m | KP |
| Mongomo | GEM | Equatorial Guinea | 344 km | 1h 0m | C2 |
| Libreville | LBV | Gabon | 373 km | 0h 50m | J7 |
| Annobon | NBN | Equatorial Guinea | 667 km | 1h 40m | C2 |
| Lagos | LOS | Nigeria | 674 km | 1h 25m | KP, LH |
| Cotonou | COO | Benin | 758 km | 1h 30m | J7 |
| Lome | LFW | Togo | 869 km | 1h 40m | C2, KP |
| Addis Ababa | ADD | Ethiopia | 3,376 km | 4h 35m | ET |
| Casablanca | CMN | Morocco | 3,689 km | 5h 15m | AT |