Simon Bolivar offers nonstop service to 6 destinations, served by 5 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Bucaramanga | BGA | Colombia | 456 km | 1h 14m | P5 |
| Medellin | MDE | Colombia | 562 km | 1h 17m | AV, P5, JA |
| Panama City | PTY | Panama | 608 km | 1h 26m | CM |
| Bogota | BOG | Colombia | 709 km | 1h 30m | AV, LA, P5, JA |
| Pereira | PEI | Colombia | 716 km | 1h 25m | AV |
| Cali | CLO | Colombia | 870 km | 1h 38m | AV, JA |