George F L Charles offers nonstop service to 16 destinations, served by 4 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Fort De France | FDF | Martinique | 63 km | 0h 25m | BW |
| Saint Vincent | SVD | Saint Vincent and the Grenadines | 96 km | 0h 40m | 5L, WM |
| Dominica | DOM | Dominica | 171 km | 0h 45m | 5L, JY |
| Bridgetown | BGI | Barbados | 193 km | 0h 45m | 5L, BW, JY |
| Pointe-a-Pitre | PTP | Guadeloupe | 255 km | 1h 5m | BW |
| Antigua | ANU | Antigua and Barbuda | 355 km | 1h 5m | 5L |
| Port Of Spain | POS | Trinidad and Tobago | 379 km | 1h 5m | BW |
| Sint Maarten | SXM | Sint Maarten | 499 km | 1h 35m | WM |