Carrasco International offers nonstop service to 44 destinations, served by 14 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Buenos Aires | AEP | Argentina | 221 km | 0h 55m | AR |
| Salto | STY | Uruguay | 419 km | 1h 5m | ZP |
| Rivera | RVY | Uruguay | 432 km | 1h 5m | ZP |
| Porto Alegre | POA | Brazil | 705 km | 1h 35m | AD |
| Florianopolis | FLN | Brazil | 1,067 km | 1h 50m | H2 |
| Asuncion | ASU | Paraguay | 1,073 km | 1h 50m | ZP |
| Santiago | SCL | Chile | 1,370 km | 2h 36m | H2, LA |
| San Carlos de Bariloche | BRC | Argentina | 1,499 km | 2h 45m | AR |
| Sao Paulo | GRU | Brazil | 1,567 km | 2h 35m | G3, LA |
| Rio De Janeiro | GIG | Brazil | 1,822 km | 2h 40m | G3, H2, JA |
| Belo Horizonte | CNF | Brazil | 2,061 km | 3h 5m | AD |
| Salvador | SSA | Brazil | 3,012 km | 4h 5m | H2 |
| Lima | LIM | Peru | 3,305 km | 4h 50m | LA |
| Recife | REC | Brazil | 3,660 km | 4h 53m | AD |
| Natal | NAT | Brazil | 3,856 km | 5h 0m | G3 |
| Fortaleza | FOR | Brazil | 3,884 km | 5h 5m | G3 |
| Bogota | BOG | Colombia | 4,770 km | 6h 40m | AV |
| Panama City | PTY | Panama | 5,447 km | 7h 29m | CM |
| Punta Cana | PUJ | Dominican Republic | 6,052 km | 8h 14m | DM |
| Miami | MIA | USA | 7,182 km | 9h 10m | AA |
| Madrid | MAD | Spain | 9,922 km | 11h 50m | IB, PU, UX |
| Barcelona | BCN | Spain | 10,310 km | 12h 45m | IB |