Silvio Pettirossi International offers nonstop service to 31 destinations, served by 9 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Jujuy | JUJ | Argentina | 770 km | 1h 40m | ZP |
| Salta | SLA | Argentina | 804 km | 1h 30m | ZP |
| Rosario | ROS | Argentina | 909 km | 1h 40m | ZP |
| Florianopolis | FLN | Brazil | 933 km | 1h 40m | ZP |
| Santa Cruz | VVI | Bolivia | 1,022 km | 1h 45m | OB, ZP |
| Buenos Aires | AEP | Argentina | 1,036 km | 1h 55m | AR, JA, ZP |
| Buenos Aires | EZE | Argentina | 1,065 km | 1h 55m | JA |
| Montevideo | MVD | Uruguay | 1,073 km | 1h 50m | ZP |
| Punta Del Este | PDP | Uruguay | 1,091 km | 1h 50m | ZP |
| Sao Paulo | GRU | Brazil | 1,137 km | 2h 5m | G3, LA |
| Rio De Janeiro | GIG | Brazil | 1,475 km | 2h 20m | G3, JA, ZP |
| Santiago | SCL | Chile | 1,572 km | 2h 50m | LA |
| Lima | LIM | Peru | 2,527 km | 3h 55m | LA |
| Bogota | BOG | Colombia | 3,769 km | 5h 20m | AV |
| Panama City | PTY | Panama | 4,475 km | 6h 9m | CM |
| Madrid | MAD | Spain | 9,169 km | 11h 5m | UX |