Darwin Intl offers nonstop service to 22 destinations, served by 8 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Katherine | KTR | Australia | 283 km | 0h 55m | TL |
| Maningrida | MNG | Australia | 367 km | 1h 5m | TL |
| Milingimbi | MGT | Australia | 438 km | 1h 10m | TL |
| Kununurra | KNX | Australia | 440 km | 1h 5m | TL |
| Elcho Island | ELC | Australia | 512 km | 1h 20m | TL |
| Groote Island | GTE | Australia | 629 km | 1h 35m | TL |
| Gove | GOV | Australia | 646 km | 1h 15m | TL |
| Mcarthur River | MCV | Australia | 719 km | 1h 30m | TL |
| Dili | DIL | East Timor | 724 km | 1h 30m | TL, QF |
| Alice Springs | ASP | Australia | 1,300 km | 2h 10m | QF |
| Cairns | CNS | Australia | 1,676 km | 2h 30m | QF |
| Denpasar | DPS | Indonesia | 1,765 km | 2h 40m | JQ, QZ |
| Townsville | TSV | Australia | 1,862 km | 2h 40m | TL |
| Adelaide | ADL | Australia | 2,612 km | 3h 45m | JQ, QF |
| Perth | PER | Australia | 2,646 km | 3h 55m | QF, VA |
| Brisbane | BNE | Australia | 2,850 km | 3h 50m | JQ, QF, VA |
| Coolangatta (Gold Coast) | OOL | Australia | 2,928 km | 3h 50m | JQ |
| Melbourne | MEL | Australia | 3,124 km | 4h 10m | JQ, QF, VA |
| Sydney | SYD | Australia | 3,149 km | 4h 25m | JQ, QF, VA |
| Singapore | SIN | Singapore | 3,339 km | 4h 50m | SQ, QF |
| Kuala Lumpur | KUL | Malaysia | 3,634 km | 5h 10m | AK |
| Guangzhou | CAN | China | 4,398 km | 6h 25m | CZ |