Adelaide International offers nonstop service to 68 destinations, served by 15 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Kingscote | KGC | Australia | 125 km | 0h 40m | QF |
| Whyalla | WYA | Australia | 229 km | 0h 50m | QF |
| Port Lincoln | PLO | Australia | 246 km | 0h 50m | QF, ZL |
| Mount Gambier | MGB | Australia | 370 km | 1h 10m | ZL |
| Broken Hill | BHQ | Australia | 424 km | 1h 15m | ZL |
| Olympic Dam | OLP | Australia | 517 km | 1h 10m | |
| Ceduna | CED | Australia | 546 km | 1h 30m | ZL |
| Avalon | AVV | Australia | 632 km | 1h 15m | JQ |
| Melbourne | MEL | Australia | 642 km | 1h 20m | JQ, QF, VA |
| Coober Pedy | CPD | Australia | 744 km | 2h 0m | ZL |
| Canberra | CBR | Australia | 971 km | 1h 40m | QF, VA |
| Launceston | LST | Australia | 1,054 km | 1h 45m | VA |
| Sydney | SYD | Australia | 1,166 km | 1h 55m | JQ, QF, VA |
| Hobart | HBA | Australia | 1,170 km | 1h 50m | JQ |
| Newcastle | NTL | Australia | 1,252 km | 2h 5m | QF |
| Alice Springs | ASP | Australia | 1,313 km | 2h 15m | QF, VA |
| Coolangatta (Gold Coast) | OOL | Australia | 1,605 km | 2h 20m | JQ, VA |
| Brisbane | BNE | Australia | 1,618 km | 2h 30m | JQ, QF, VA |
| Sunshine Coast | MCY | Australia | 1,668 km | 2h 35m | JQ |
| Perth | PER | Australia | 2,121 km | 3h 25m | JQ, QF, VA |
| Cairns | CNS | Australia | 2,125 km | 3h 0m | JQ |
| Darwin | DRW | Australia | 2,612 km | 3h 50m | JQ, QF |
| Christchurch | CHC | New Zealand | 3,061 km | 4h 0m | NZ |
| Auckland | AKL | New Zealand | 3,257 km | 4h 20m | NZ, QF, QR |
| Denpasar | DPS | Indonesia | 3,752 km | 5h 20m | JQ |
| Nadi | NAN | Fiji | 4,289 km | 5h 10m | FJ |
| Singapore | SIN | Singapore | 5,393 km | 7h 0m | SQ |
| Kuala Lumpur | KUL | Malaysia | 5,671 km | 7h 45m | MH |
| Hong Kong | HKG | Hong Kong SAR | 6,848 km | 8h 45m | CX |
| Guangzhou | CAN | China | 6,983 km | 9h 5m | CZ |
| Shanghai | PVG | China | 7,521 km | 10h 15m | MU |
| Dubai | DXB | United Arab Emirates | 10,997 km | 13h 10m | EK |
| Doha | DOH | Qatar | 11,312 km | 13h 30m | QR |
| San Francisco | SFO | USA | 12,985 km | 14h 55m | UA |