Alice Springs offers nonstop service to 16 destinations, served by 3 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Tennant Creek | TCA | Australia | 461 km | 1h 10m | TL |
| Darwin | DRW | Australia | 1,300 km | 2h 5m | QF |
| Adelaide | ADL | Australia | 1,313 km | 2h 0m | QF, VA |
| Cairns | CNS | Australia | 1,454 km | 2h 10m | TL |
| Melbourne | MEL | Australia | 1,857 km | 2h 40m | QF |
| Brisbane | BNE | Australia | 1,967 km | 2h 55m | QF |
| Perth | PER | Australia | 1,979 km | 3h 15m | TL |
| Sydney | SYD | Australia | 2,020 km | 2h 45m | QF |