Charlottetown offers nonstop service to 15 destinations, served by 5 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Montreal | YHU | Canada | 802 km | 1h 55m | PD |
| Montreal | YUL | Canada | 828 km | 1h 39m | AC |
| Ottawa | YOW | Canada | 979 km | 2h 13m | PD |
| Toronto | YYZ | Canada | 1,328 km | 2h 23m | AC, F8, PD |
| Punta Cana | PUJ | Dominican Republic | 3,112 km | 4h 40m | TS |
| Cancun | CUN | Mexico | 3,533 km | 5h 50m | TS |
| Edmonton | YEG | Canada | 3,635 km | 5h 25m | WS |
| Calgary | YYC | Canada | 3,706 km | 5h 30m | WS |