Iqaluit offers nonstop service to 25 destinations, served by 2 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Pangnirtung | YXP | Canada | 296 km | 1h 0m | 5T |
| Cape Dorset | YTE | Canada | 394 km | 1h 15m | 5T |
| Qikiqtarkuaq | YVM | Canada | 470 km | 1h 35m | 5T |
| Kuujjuaq | YVP | Canada | 629 km | 1h 15m | 5T |
| Clyde River | YCY | Canada | 743 km | 2h 0m | 5T |
| Hall Beach | YUX | Canada | 797 km | 2h 10m | 5T |
| Nuuk | GOH | Greenland | 822 km | 2h 10m | GL |
| Igloolik | YGT | Canada | 859 km | 2h 0m | 5T |
| Pond Inlet | YIO | Canada | 1,067 km | 2h 25m | 5T |
| Rankin Inlet | YRT | Canada | 1,180 km | 2h 5m | 5T |
| Arctic Bay | YAB | Canada | 1,225 km | 2h 45m | 5T |
| Ottawa | YOW | Canada | 2,099 km | 3h 15m | 5T |