Del Caribe International Gen Santago Marino offers nonstop service to 10 destinations, served by 4 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Puerto Ordaz | PZO | Venezuela | 319 km | 0h 50m | V0 |
| Caracas | CCS | Venezuela | 334 km | 0h 50m | V0, 9V, 5R |
| Valencia | VLN | Venezuela | 440 km | 1h 0m | T9, V0 |
| Barquisimeto | BRM | Venezuela | 597 km | 0h 50m | V0 |
| Valera | VLV | Venezuela | 745 km | 1h 30m | V0 |
| Maracaibo | MAR | Venezuela | 849 km | 1h 20m | V0 |
| El Vigia | VIG | Venezuela | 879 km | 1h 20m | V0 |
| La Fria | LFR | Venezuela | 958 km | 1h 20m | V0 |
| Santo Domingo | STD | Venezuela | 961 km | 1h 25m | V0 |
| San Antonio del Tachira | SVZ | Venezuela | 990 km | 1h 40m |