El Plumerillo offers nonstop service to 26 destinations, served by 7 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Santiago | SCL | Chile | 196 km | 1h 0m | H2, JA, LA |
| Cordoba | COR | Argentina | 464 km | 1h 5m | AR |
| Neuquen | NQN | Argentina | 682 km | 1h 25m | AR |
| Salta | SLA | Argentina | 942 km | 1h 40m | AR, JA |
| San Carlos de Bariloche | BRC | Argentina | 946 km | 1h 45m | AR, JA |
| Buenos Aires | EZE | Argentina | 974 km | 1h 40m | AR, JA |
| Buenos Aires | AEP | Argentina | 981 km | 1h 40m | AR, JA |
| Mar Del Plata | MDQ | Argentina | 1,165 km | 1h 50m | AR |
| Sao Paulo | GRU | Brazil | 2,420 km | 3h 30m | G3, LA |
| Lima | LIM | Peru | 2,455 km | 3h 50m | LA |
| Rio De Janeiro | GIG | Brazil | 2,741 km | 3h 38m | JA |
| Panama City | PTY | Panama | 4,770 km | 6h 52m | CM |
| Punta Cana | PUJ | Dominican Republic | 5,687 km | 7h 43m | DM |