Luxor International offers nonstop service to 43 destinations, served by 13 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Marsa Alam | RMF | Egypt | 190 km | 0h 40m | NO |
| Hurghada | HRG | Egypt | 200 km | 1h 5m | SM |
| Sharm el Sheikh | SSH | Egypt | 305 km | 1h 0m | NO, SM, WK |
| Cairo | CAI | Egypt | 508 km | 1h 10m | MS, NE, NO, NP, SM |
| Madinah | MED | Saudi Arabia | 716 km | 1h 20m | SM |
| Jeddah | JED | Saudi Arabia | 793 km | 1h 35m | DQ, MS, NE, SM |
| Kuwait | KWI | Kuwait | 1,559 km | 2h 35m | J9 |
| Athens | ATH | Greece | 1,590 km | 2h 30m | A3 |
| Istanbul | SAW | Turkiye | 1,718 km | 2h 45m | PC |
| Milan | MXP | Italy | 3,077 km | 4h 45m | NO, U2 |
| Lyon | LYS | France | 3,315 km | 5h 0m | U2 |
| Dusseldorf | DUS | Germany | 3,593 km | 5h 15m | X3 |
| Paris | ORY | France | 3,669 km | 5h 30m | TO |
| Paris | CDG | France | 3,674 km | 5h 35m | SM, U2 |
| Nantes | NTE | France | 3,840 km | 5h 35m | U2 |
| London | LGW | United Kingdom | 3,969 km | 5h 45m | U2 |
| London | LHR | United Kingdom | 4,004 km | 5h 45m | MS |
| Manchester | MAN | United Kingdom | 4,223 km | 6h 20m |