Marsa Alam Airport offers nonstop service to 31 destinations, served by 17 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Luxor | LXR | Egypt | 190 km | 0h 50m | NO |
| Hurghada | HRG | Egypt | 197 km | 0h 35m | LG |
| Sharm el Sheikh | SSH | Egypt | 269 km | 0h 50m | NO, TB |
| Cairo | CAI | Egypt | 595 km | 1h 20m | MS |
| Istanbul | SAW | Turkiye | 1,771 km | 2h 55m | PC |
| Naples | NAP | Italy | 2,532 km | 4h 10m | U2, NO |
| Rome | FCO | Italy | 2,729 km | 4h 20m | NO, W4 |
| Vienna | VIE | Austria | 2,959 km | 4h 15m | SM |
| Bologna | BLQ | Italy | 2,970 km | 4h 35m | NO |
| Ostrava | OSR | Czech Republic | 3,033 km | 4h 25m | QS |
| Brno | BRQ | Czech Republic | 3,043 km | 4h 30m | QS |
| Verona | VRN | Italy | 3,054 km | 4h 35m | NO, AP |
| Salzburg | SZG | Austria | 3,110 km | 4h 55m | EW |
| Milan | BGY | Italy | 3,147 km | 4h 50m | NO |
| Milan | MXP | Italy | 3,206 km | 4h 50m | NO, AP, U2, W4 |
| Munich | MUC | Germany | 3,218 km | 4h 55m | X3, SM |
| Prague | PRG | Czech Republic | 3,236 km | 4h 50m | QS |
| Zurich | ZRH | Switzerland | 3,336 km | 5h 5m | WK, W2, SM, CS |
| Nuremberg | NUE | Germany | 3,343 km | 5h 0m | EW |
| Stuttgart | STR | Germany | 3,386 km | 5h 0m | X3, SM, EW |
| Geneva | GVA | Switzerland | 3,412 km | 5h 10m | U2 |
| Berlin | BER | Germany | 3,464 km | 5h 10m | U2, EW |
| Frankfurt | FRA | Germany | 3,518 km | 5h 20m | X3, SM |
| Luxembourg | LUX | Luxembourg | 3,621 km | 5h 20m | LG |
| Hanover | HAJ | Germany | 3,644 km | 5h 15m | X3, SM |
| Cologne | CGN | Germany | 3,656 km | 5h 20m | SM, EW |
| Dusseldorf | DUS | Germany | 3,704 km | 5h 30m | X3, EW, SM |
| Hamburg | HAM | Germany | 3,724 km | 5h 25m | EW |
| Brussels | BRU | Belgium | 3,804 km | 6h 10m | TB |
| Amsterdam | AMS | Netherlands | 3,884 km | 5h 50m | OR, HV |
| London | LGW | United Kingdom | 4,092 km | 6h 5m |