Deer Lake offers nonstop service to 8 destinations, served by 4 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| St. John's | YYT | Canada | 387 km | 1h 10m | PB |
| Goose Bay | YYR | Canada | 502 km | 1h 20m | PB |
| Moncton | YQM | Canada | 646 km | 1h 50m | PB |
| Halifax | YHZ | Canada | 668 km | 1h 39m | AC, PD |
| Montreal | YUL | Canada | 1,301 km | 2h 13m | AC |
| Ottawa | YOW | Canada | 1,444 km | 2h 35m | PD |
| Toronto | YYZ | Canada | 1,805 km | 3h 5m | AC, PD |
| Calgary | YYC | Canada | 3,948 km | 5h 45m | WS |