Maotai Airport offers nonstop service to 25 destinations, served by 9 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Guiyang | KWE | China | 161 km | 1h 0m | GY, G5 |
| Chongqing | CKG | China | 195 km | 0h 50m | G5 |
| Xingyi | ACX | China | 351 km | 1h 0m | GY |
| Yichang | YIH | China | 567 km | 1h 13m | G5 |
| Lijiang | LJG | China | 628 km | 1h 35m | PN |
| Dali City | DLU | China | 659 km | 1h 20m | 8L |
| Xian | XIY | China | 751 km | 1h 25m | GS |
| Zhanjiang | ZHA | China | 846 km | 1h 38m | G5 |
| Guangzhou | CAN | China | 854 km | 1h 50m | CZ |
| Jinghong | JHG | China | 875 km | 1h 40m | 8L |
| Nanchang | KHN | China | 933 km | 1h 45m | GY |
| Shenzhen | SZX | China | 947 km | 2h 0m | CZ |
| Haikou | HAK | China | 978 km | 1h 40m | GS |
| Zhengzhou | CGO | China | 1,012 km | 1h 55m | PN |
| Hefei | HFE | China | 1,110 km | 2h 5m | GY |
| Xiamen | XMN | China | 1,227 km | 2h 10m | MF |
| Jinjiang | JJN | China | 1,261 km | 2h 8m | MF |
| Nanjing | NKG | China | 1,271 km | 2h 10m | GY |
| Shijiazhuang | SJW | China | 1,378 km | 2h 23m | 8L |
| Hangzhou | HGH | China | 1,384 km | 2h 25m | MF |
| Jinan | TNA | China | 1,412 km | 2h 25m | GY |
| Ningbo | NGB | China | 1,479 km | 2h 20m | 8L |
| Lhasa/Lasa | LXA | China | 1,523 km | 3h 0m | PN |
| Shanghai | PVG | China | 1,529 km | 2h 30m | MU |
| Beijing | PEK | China | 1,636 km | 2h 40m | CA |