Maotai Airport offers nonstop service to 43 destinations, served by 9 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Guiyang | KWE | China | 161 km | 0h 40m | G5 |
| Chongqing | CKG | China | 195 km | 0h 55m | G5 |
| Yichang | YIH | China | 567 km | 1h 10m | G5 |
| Lijiang | LJG | China | 628 km | 1h 35m | PN |
| Dali City | DLU | China | 659 km | 1h 30m | 8L |
| Xian | XIY | China | 751 km | 1h 30m | GS |
| Wuhan | WUH | China | 817 km | 1h 35m | GJ |
| Zhanjiang | ZHA | China | 846 km | 1h 45m | G5 |
| Guangzhou | CAN | China | 854 km | 1h 50m | CZ |
| Jinghong | JHG | China | 875 km | 1h 40m | 8L |
| Mangshi | LUM | China | 882 km | 1h 38m | PN |
| Shenzhen | SZX | China | 947 km | 2h 0m | CZ |
| Haikou | HAK | China | 978 km | 2h 0m | GS |
| Zhengzhou | CGO | China | 1,012 km | 1h 55m | PN |
| Xiamen | XMN | China | 1,227 km | 2h 5m | MF |
| Jinjiang | JJN | China | 1,261 km | 2h 15m | MF |
| Shijiazhuang | SJW | China | 1,378 km | 2h 20m | 8L |
| Hangzhou | HGH | China | 1,384 km | 2h 20m | MF |
| Ningbo | NGB | China | 1,479 km | 2h 30m | 8L |
| Lhasa/Lasa | LXA | China | 1,523 km | 2h 50m | PN |
| Shanghai | PVG | China | 1,529 km | 2h 40m | MU |
| Beijing | PEK | China | 1,636 km | 2h 40m | CA |