Khomutovo offers nonstop service to 18 destinations, served by 4 airlines.
| Destination | Code | Country | Distance | Duration | Airlines |
|---|---|---|---|---|---|
| Shakhtyorsk | EKS | Russia | 260 km | 1h 10m | HZ |
| Sovetskaya Gavan | GVN | Russia | 302 km | 1h 25m | HZ |
| Kunashir Island | DEE | Russia | 399 km | 1h 15m | HZ |
| Tymovskoye | ZZO | Russia | 420 km | 1h 50m | HZ |
| Iturup Island | ITU | Russia | 443 km | 1h 5m | HZ |
| Aleksandrovsk-Sakhalinkiy | UHS | Russia | 445 km | 2h 0m | HZ |
| Nogliki | NGK | Russia | 545 km | 1h 40m | HZ |
| Khabarovsk | KHV | Russia | 595 km | 1h 20m | SU, IO |
| Okha | OHH | Russia | 737 km | 2h 0m | HZ |
| Vladivostok | VVO | Russia | 916 km | 1h 45m | S7, SU |
| Blagoveschensk | BQS | Russia | 1,192 km | 2h 10m | HZ |
| Harbin | HRB | China | 1,276 km | 2h 28m | HZ |
| Petropavlovsk-Kamchatsky | PKC | Russia | 1,321 km | 2h 20m | HZ |
| Beijing | PKX | China | 2,276 km | 3h 55m | HZ |
| Ulan-Ude | UUD | Russia | 2,590 km | 3h 45m | IO |
| Krasnojarsk | KJA | Russia | 3,547 km | 5h 10m | HZ |
| Novosibirsk | OVB | Russia | 4,178 km | 6h 5m | S7 |
| Moscow | SVO | Russia | 6,662 km | 8h 35m | SU |